G1514

D-(+)-Glucosamin -hydrochlorid

≥99%, BioReagent, suitable for cell culture

• Synonym(e): 2-Amino-2-deoxy-D-glucose -hydrochlorid, Chitosamin -hydrochlorid
• Empirische Formel (Hill-System): C₆H₁₃NO₅ · HCl
• CAS-Nummer: 66-84-2
• Molekulargewicht: 215.63
• Beilstein: 4157370
• EG-Nummer: 200-638-1
• MDL-Nummer: MFCD00135831
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24895066
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: Aspergillus niger; maize fruit
• Qualitätsniveau: 200
• Produktlinie: BioReagent
• Assay: ≥99%
• Form: powder
• Methode(n): cell culture | mammalian: suitable
• mp (Schmelzpunkt): 190-194 °C (dec.) (lit.)
• Löslichkeit: water: 100 mg/mL, clear, colorless
• SMILES String: Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1
• InChIKey: QKPLRMLTKYXDST-NSEZLWDYSA-N

Beschreibung

Allgemeine Beschreibung

Glucosamine, an amino sugar is generated form glucose and glutamine[1] and is naturally produced in the body.[2] Glucosamine, a endogenous amino monosaccharide[2] is the major source of glucosamine-6-phosphate and n-acetylglucosamine.[1]

Anwendung

Glucosamine has been used as a standard to examine the concentration of glucosamine in the synovial fluid and its pharmacokinetics in serum.[3]

Biochem./physiol. Wirkung

Glucosamine is preferred as a nutritional supplement for individuals with osteoarthritis.[4] It is used as a building block for the production of proteoglycans and glycosaminoglycans.[2]

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)