F112

(+)-Fenfluramine hydrochloride

serotonin uptake inhibitor, powder

• Synonym(e): (+)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride, Dexfenfluramine hydrochloride
• Empirische Formel (Hill-System): C₁₂H₁₆F₃N · HCl
• CAS-Nummer: 3239-45-0
• Molekulargewicht: 267.72
• NACRES: NA.77
• PubChem Substance ID: 24894746
• UNSPSC Code: 12352116
• EC Number: 221-806-0
• MDL number: MFCD00069276
• Form: powder

Eigenschaften

• Produktname: (+)-Fenfluramine hydrochloride,
• form: powder
• Quality Segment: 200
• drug control: USDEA Schedule IV
• color: white to off-white
• solubility: H₂O: soluble 10 mg/mL
• application(s): forensics and toxicology
• storage temp.: room temp
• SMILES string: Cl[H].CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F
• InChI: 1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m0./s1
• InChI key: ZXKXJHAOUFHNAS-FVGYRXGTSA-N
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR6(3362), HTR7(3363)

Beschreibung

Biochem/physiol Actions

(+)-Fenfluramine is a serotonin uptake inhibitor; anoxexic.

(+)-Fenfluramine is a serotonin uptake inhibitor; anoxexic. (+)-Fenfluramine is neurotoxic on prolonged administration or at high dosage. (+)-Fenfluramine releases serotonin from axon terminals by a nonexocytotic mechanism.

Other Notes

Active isomer

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H301 + H311 + H331
• pcodes: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges