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Merck

C7519

Sigma-Aldrich

Cholin-Bikarbonat

~80% in H2O

Synonym(e):

2-(Hydroxyethyl)-trimethylammonium-bicarbonat

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100 ML
149,00 €
250 ML
289,00 €
500 ML
497,00 €

149,00 €


Versandbereit am07. April 2025Details


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100 ML
149,00 €
250 ML
289,00 €
500 ML
497,00 €

About This Item

Lineare Formel:
C5H14NO · HCO3
CAS-Nummer:
Molekulargewicht:
165.19
MDL-Nummer:
UNSPSC-Code:
50501514
PubChem Substanz-ID:
NACRES:
NA.25

149,00 €


Versandbereit am07. April 2025Details


Bulk-Bestellung anfordern

Form

liquid

Konzentration

~80% in H2O

Dichte

1.17 g/mL at 25 °C (lit.)

Lipid-Typ

phospholipids

Lagertemp.

2-8°C

SMILES String

OC([O-])=O.C[N+](C)(C)CCO

InChI

1S/C5H14NO.CH2O3/c1-6(2,3)4-5-7;2-1(3)4/h7H,4-5H2,1-3H3;(H2,2,3,4)/q+1;/p-1

InChIKey

DQKGOGJIOHUEGK-UHFFFAOYSA-M

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Anwendung

Cholin, ein essenzieller wasserlöslicher Nährstoff, wird vom Körper zur Erzeugung von Phosphatidylcholin-Phosphatiden und Neurotransmittern wie Acetylcholin verwendet. Cholin wird für Untersuchungen eines breiten Spektrums biologischer Prozesse von der Stammzellenentwicklung bis zur Erforschung von neurologischen Krankheiten eingesetzt. Darüber hinaus ist ein alkalisches Zwischenprodukt für die Salzherstellung von Nutzen.

Biochem./physiol. Wirkung

Acylgruppenakzeptor

Substrate

Cholin-Acetyltransferase-Substrat

Sonstige Hinweise

Hinweis: Das Bicarbonate wird mit der alterungsbedingten Freisetzung von CO2 in Carbonat konvertiert.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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In the present research work, we propose a new antimicrobial treatment for pyoderma via cutaneous permeation of bacteriophage particles conveyed in a hydroxyethylcellulose (HEC) gel integrating ionic liquid as a permeation enhancer. Ionic liquids are highly viscous fluids constituted exclusively
Karen D Corbin et al.
Progress in molecular biology and translational science, 108, 159-177 (2012-06-05)
Advances in nutrigenetics and nutrigenomics have been instrumental in demonstrating that nutrient requirements vary among individuals. This is exemplified by studies of the nutrient choline, in which gender, single-nucleotide polymorphisms, estrogen status, and gut microbiome composition have been shown to
Hussain Mohamad Awwad et al.
Clinical biochemistry, 45(18), 1548-1553 (2012-08-28)
Choline is an essential nutrient that is necessary for cell membrane synthesis and phospholipid metabolism and functions as an important methyl donor. Multiple roles for choline in cancer development have been suggested. Choline can affect DNA methylation and lead to
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Psychotherapy and psychosomatics, 82(1), 10-19 (2012-11-14)
Pharmacotherapy is the first line of treatment for bipolar disorder, but many patients continue to experience persistent subthreshold symptoms. Alternative adjunct treatments, including nutritional therapies, may have the potential to alleviate residual symptoms and improve the outcomes of standard pharmacotherapy.
Ludmilla R Jorge et al.
Frontiers in pharmacology, 11, 243-243 (2020-05-12)
In this research project, synthesis and characterization of ionic liquids and their subsequent utilization as facilitators of transdermal delivery of human insulin was pursued. Choline geranate and choline oleate ionic liquids (and their deep eutectic solvents) were produced and characterized

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 Antwort
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 Antwort
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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