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Merck

C6719

Sigma-Aldrich

Crotonöl

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352211
NACRES:
NA.25
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Biologische Quelle

plant (Croton tiglium L)

Qualitätsniveau

Form

viscous liquid

Dichte

0.94 g/mL at 25 °C (lit.)

Funktionelle Gruppe

ester

Lipid-Typ

oils

Versandbedingung

ambient

Lagertemp.

room temp

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Allgemeine Beschreibung

Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature.[1] Croton oil has a strong irritant property[1] and is used along with phenol in some chemical peels.[2] It also has a tumor promoting ability.[3]
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma.[4] Croton oil functions as a skin peeling agent.[5]

Anwendung

Croton oil has been used to induce acute skin inflammation.[6]
Croton oil has been used to induce inflammation in mouse ears.[7][6][8]

Sonstige Hinweise

Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

165.2 °F - closed cup

Flammpunkt (°C)

74 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Direct effect of croton oil on intestinal epithelial cells and colonic smooth muscle cells
Wang X, et al.
World Journal of Gastroenterology, 8(1), 103-103 (2002)
Protein Kinase C in Oncogenic Transformation and Cell Polarity
Signal Transduction (2016)
Thekkuttuparambil Ananthanarayanan Ajith et al.
Journal of experimental therapeutics & oncology, 9(3), 207-215 (2011-11-11)
The roles of 7,12-dimethylbenz[a]anthracene (DMBA), a polycyclic aromatic hydrocarbon (PAH), and 12-O-tetradecanoylphorbol-13-acetate (TPA) a skin tumor promoter present in croton oil, are clearly implicated in the formation of skin papilloma. The effect of ethyl acetate extract of Phellinus rimosus, a
Alireza Garjani et al.
Iranian biomedical journal, 16(2), 59-67 (2012-07-18)
A growing body of preclinical data indicates that statins may possess antineoplastic properties; however, some studies have raised the possibility that statins may also have carcinogenic potential. An air pouch model was used for angiogenesis. Single or multiple applications of
Effects of Haruan (Channa striatus) Based Cream on Acute Inflammation in Croton Oil Induced Mice Ear Edema Model
Abedi S, et al.
Research Journal of Biological Sciences, 7(4), 181-187 (2012)

Fragen

  1. What’s the origin of this croton tigliun oil?

    1 Antwort
    1. The product is extracted from Croton tiglium, a plant commonly known as purging croton. Although the country of origin may change, the material typically originates from China. Please see the link below to review a sample Certificate of Origin:
      https://www.sigmaaldrich.com/US/en/coo/undefined/C6719/MKBK0847V

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