C4743

Monoclonal Anti-Cytochrome P450 3A5 in Maus hergestellte Antikörper

~2 mg/mL, clone F18 P3 B6, purified immunoglobulin, buffered aqueous solution

• Synonym(e): Anti-CP35, Anti-CYP3A5, Anti-P450PCN3, Anti-PCN3
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: F18 P3 B6, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen ~55 kDa
• Speziesreaktivität: human
• Konzentration: ~2 mg/mL
• Methode(n): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: 0.5-1.0 μg/mL using human recombinant cytochrome P450 3A5.
• Isotyp: IgG1
• UniProt-Hinterlegungsnummer: P20815
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CYP3A5(1577)

Beschreibung

Spezifität

The antibody does not cross react with cytochrome P450 3A4 or 3A7.

Immunogen

synthetic peptide corresponding to amino acids 380-389 of human cytochrome P450 3A5.

Anwendung

Monoclonal Anti-Cytochrome P450 3A5 antibody produced in mouse is suitable for:

• immunohistochemistry
• indirect ELISA
• western blotting at a concentration of 0.5-1.0 μg/mL using human recombinant cytochrome P450 3A5

Biochem./physiol. Wirkung

Cytochrome P450 enzymes are a super family of heme containing mono-oxygenases that in humans are involved with oxidative metabolism of xenobiotics. This metabolism is the initial step in the biotransformation and elimination of a wide variety of drugs and environmental pollutants from the body. The Cytochrome P450 3A (CYP 3A) family contains several isoforms with the CYP 3A4 isoform contributing most of the family activity and the CYP 3A5, 3A7 and 3A43 being the minor isoforms.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter