A9376

Adenosin-2′:3′-zyklisches Monophosphat Natriumsalz

≥93%

• Synonym(e): 2′,3′-cAMP sodium salt
• Lineare Formel: C₁₀H₁₁N₅O₆PNa
• CAS-Nummer: 37063-35-7
• Molekulargewicht: 351.19
• EG-Nummer: 253-328-3
• MDL-Nummer: MFCD00005757
• UNSPSC-Code: 41106305
• eCl@ss: 32160414
• PubChem Substanz-ID: 24891439
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥93%
• Form: powder
• Löslichkeit: water: 50 mg/mL, clear, colorless
• Lagertemp.: −20°C
• SMILES String: [Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H]4OP([O-])(=O)O[C@@H]34
• InChI: 1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7-6(4(1-16)19-10)20-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
• InChIKey: VSDSIACSNXHGOV-MCDZGGTQSA-M

Beschreibung

Anwendung

Adenosine 2′:3′-cyclic monophosphate sodium salt has been used in lysis buffer for affinity purification and also in microscale thermophoresis measurements. It has also been used in electrophysiological studies of Tenebrio tubules.

Biochem./physiol. Wirkung

Adenosine 2′,3′-cyclic monophosphate (2′,3′-cAMP) is believed to serve as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.

Vorsicht

Caution: Do not confuse with the common adenosine 2′(3′)-monophosphate (mixed isomers).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable