A9062

Adenosin-5′-Triphosphat Bis-(Tris)-salz Hydrat

≥95%

• Synonym(e): 5′-ATP-Bis(TRIS)
• Empirische Formel (Hill-System): C₁₀H₁₆N₅O₁₃P₃ · 2C₄H₁₁NO₃ · xH₂O
• CAS-Nummer: 102047-34-7
• Molekulargewicht: 749.45 (anhydrous basis)
• UNSPSC-Code: 41106305
• eCl@ss: 32160414
• PubChem Substanz-ID: 24891222
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: (Fermentation)
• Assay: ≥95%
• Form: powder
• Löslichkeit: H₂O: 50 mg/mL
• Kationenspuren: Na: ≤0.1%
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: O.NC(CO)(CO)CO.NC(CO)(CO)CO.Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2C4H11NO3.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;2*5-4(1-6,2-7)3-8;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);2*6-8H,1-3,5H2;1H2/t4-,6-,7-,10-;;;/m1.../s1
• InChIKey: ZMNHJZFDZFGOFE-MSQVLRTGSA-N

Beschreibung

Anwendung

Adenosine 5′-triphosphate di(tris) salt hydrate has been used:

• to treat cells for Ca²⁺ influx measurements in stromal interaction molecule 1 knockout (STIM1−/−) mice and in vitro chemotaxis assay for microglial migration
• supplemented in buffer C for mitochondrial respiratory control assay and complex V activity assay
• in the inhibition of silver nano particles (AgNPs) on Na⁺/K⁺-ATPase activity

Biochem./physiol. Wirkung

Adenosine 5′-triphosphate di(tris) salt dehydrate is useful in applications that require the absence of metals.
Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.

P₂ purinergener Antagonist; erhöht die Aktivität von Ca²⁺-aktivierten K⁺ Kanälen; Substrat für ATP-abhängigen Enzymsysteme.

Vorsicht

Unstable: For maximum stability, store as frozen solution at pH 3.5 to 6.8.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves