95144

Retinol

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

• Synonym(e): Axerophthol, Vitamin A, Vitamin A₁, Vitamin-A-alkohol, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
• Empirische Formel (Hill-System): C₂₀H₃₀O
• CAS-Nummer: 68-26-8
• Molekulargewicht: 286.45
• Beilstein: 403040
• EG-Nummer: 200-683-7
• MDL-Nummer: MFCD00001552
• UNSPSC-Code: 12352205
• eCl@ss: 34058018
• PubChem Substanz-ID: 57653654
• NACRES: NA.28

Eigenschaften

• Biologische Quelle: synthetic
• Produktlinie: BioXtra
• Assay: ≥97.5% (HPLC)
• Form: (Powder or Powder with Lumps)
• Spezifische Aktivität: ~3100 U/mg
• Haltbarkeit: limited shelf life
• Farbe: faint yellow to very dark yellow
• mp (Schmelzpunkt): 56-61 °C; 61-63 °C (lit.)
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1
• InChI: 1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
• InChIKey: FPIPGXGPPPQFEQ-OVSJKPMPSA-N

Beschreibung

Allgemeine Beschreibung

Retinol or vitamin A alcohol is the main circulating form of vitamin A.

Anwendung

Retinol has been used:

• as a standard in peak identification and quantification in reverse phase HPLC
• as a standard to estimate the concentration of vitamin A
• to study the inhibitory effect of retinol on murine norovirus (MNV) replication in murine RAW 264.7 cells
• as a component in the reaction mixture for the lecithin:retinol acyltransferase (LRAT) assay

Biochem./physiol. Wirkung

It is not biologically active and works as a precursor of active retinoids. Retinol is converted to retinaldehyde and subsequently to retinoic acid.

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinol is biological active in a wide range of processes.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Einheitendefinition

1 U entspricht 1 Internationalen Einheit gemäss Ph Eur II, 217 (1983)

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H317,H319,H360FD,H413
• P-Sätze: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves