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Sigma-Aldrich

N,N-Bis-[3-(D-gluconamido)-propyl]-deoxycholamid

≥90% (HPLC)

Synonym(e):

deoxy-BigCHAP

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About This Item

Empirische Formel (Hill-System):
C42H75N3O15
CAS-Nummer:
86303-23-3
Molekulargewicht:
862.06
UNSPSC-Code:
12161902
PubChem Substanz-ID:
57647220
NACRES:
NA.77

Beschreibung

non-ionic

Assay

≥90% (HPLC)

Mol-Gew.

micellar average mol wt 10,500

Aggregatnummer

8-16

Verunreinigungen

≤4% water

CMC

1.1-1.4 mM (20-25°C)

Lagertemp.

2-8°C

SMILES String

O=C(N(CCCNC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)CCCNC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)CC[C@@H](C)[C@]1([H])[C@@]2(C)[C@@H](O)C[C@@]3([H])C([C@]2([H])CC1)CC[C@]4([H])C[C@H](O)CC[C@@]43C

InChI

1S/C42H75N3O15/c1-22(26-9-10-27-25-8-7-23-18-24(48)12-13-41(23,2)28(25)19-31(51)42(26,27)3)6-11-32(52)45(16-4-14-43-39(59)37(57)35(55)33(53)29(49)20-46)17-5-15-44-40(60)38(58)36(56)34(54)30(50)21-47/h22-31,33-38,46-51,53-58H,4-21H2,1-3H3,(H,43,59)(H,44,60)/t22-,23-,24-,25+,26-,27+,28+,29-,30-,31+,33-,34-,35+,36+,37-,38-,41+,42-/m1/s1

InChIKey

OJSUWTDDXLCUFR-HGZMBBKESA-N

Anwendung

N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide is used for membrane solubilisation and proteomic analysis.

Biochem./physiol. Wirkung

N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide (deoxy-BigCHAP) is a non-ionic detergent that solubilizes cell membrane.

Angaben zur Herstellung

N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide yields a clear, colorless solution in water at 50 mg/ml.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

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Individual dissolution of single-walled carbon nanotubes in aqueous solutions of steroid or sugar compounds and their Raman and near-IR spectral properties.
Ishibashi A, Nakashima N.
Chemistry (Easton), 12, 7595-7602 (2006)
A Aigner et al.
The Biochemical journal, 317 ( Pt 1), 213-218 (1996-07-01)
Microsomal cysteine-S-conjugate N-acetyltransferase catalyses the N-acetylation of various S-substituted cysteines in liver and kidney. We describe here the purification and more detailed characterization of this enzyme catalysing the final reaction of mercapturic acid biosynthesis, and thus playing a crucial role
The Use of Detergents to Purify Membrane Protein
Arnold T and Linke D
Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.], UNIT 4.8, doi: 10-doi: 10 (2008)
L M Hjelmeland et al.
Analytical biochemistry, 130(2), 485-490 (1983-04-15)
Detergents containing either a cholic acid, a deoxycholic acid, or an octanoic acid-like hydrophobic moiety and a bisgluconamidopropyl polar group were synthesized. Extinction coefficients, partial specific volumes, critical micelle concentrations, and aggregation numbers were determined for each of the detergents.

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