Y0001778

Rabeprazol für die Systemeignung

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): Rabeprazol Natriumsalz, 2-{[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]-methylsulfinyl}-1H-benzo[d]imidazol Natriumsalz
• Empirische Formel (Hill-System): C₁₈H₂₀N₃O₃S · Na
• CAS-Nummer: 117976-90-6
• Molekulargewicht: 381.42
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: rabeprazole
• Hersteller/Markenname: EDQM
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C
• InChI: 1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1
• InChIKey: KRCQSTCYZUOBHN-UHFFFAOYSA-N
• Angaben zum Gen: human ... ATP4A(495) , ATP4B(496)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Rabeprazole for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H413
• P-Sätze: P264 - P270 - P273 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 4
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable