P4722

Pyridoxin -hydrochlorid

meets USP testing specifications

• Synonym(e): Adermin -hydrochlorid, PN HCl, Pyridoxol -hydrochlorid, Vitamin B₆ -hydrochlorid
• Empirische Formel (Hill-System): C₈H₁₁NO₃ · HCl
• CAS-Nummer: 58-56-0
• Molekulargewicht: 205.64
• Beilstein: 3632435
• EG-Nummer: 200-386-2
• MDL-Nummer: MFCD00012807
• UNSPSC-Code: 12352205
• eCl@ss: 34058008
• PubChem Substanz-ID: 24898493
• NACRES: NA.21

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 200
• Agentur: USP/NF; meets USP testing specifications
• Assay: 98.0-102.0% dry basis
• Form: powder
• Farbe: white
• mp (Schmelzpunkt): 214-215 °C (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• SMILES String: Cl[H].Cc1ncc(CO)c(CO)c1O
• InChI: 1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
• InChIKey: ZUFQODAHGAHPFQ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Vitamin B group is water-soluble and exists in six forms namely the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. The food sources of vitamin B₆ include grains, nuts, fruits, vegetables and meat.

Anwendung

Pyridoxine hydrochloride has been used to test its neuroprotective functionality in traumatic brain injury (TBI) rats. It has also been used as a reference standard to quantify vitamin B₆ in feed and digesta samples using high-performance liquid chromatography(HPLC).

Biochem./physiol. Wirkung

Pyridoxine plays a key role in metabolism both carbohydrates and amino acids. It supports brain development and its deficiency levels may lead to depletion of γ-aminobutyric acid (GABA) levels. Pyridoxine catalyzes the neurotransmitter biosynthesis like dopamine and serotonin. Pyridoxine in excess or deficient may lead to neuropathy.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H318
• P-Sätze: P280 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)