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P6280

Sigma-Aldrich

Pyridoxin -hydrochlorid

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Synonym(e):

Adermin -hydrochlorid, PN HCl, Pyridoxol -hydrochlorid, Vitamin B6 -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C8H11NO3 · HCl
CAS-Nummer:
58-56-0
Molekulargewicht:
205.64
Beilstein:
3632435
EG-Nummer:
200-386-2
MDL-Nummer:
MFCD00012807
UNSPSC-Code:
12161900
eCl@ss:
34058008
PubChem Substanz-ID:
24898752
NACRES:
NA.21

Produktlinie

BioReagent

Qualitätsniveau

200

Assay

≥98% (HPLC)

Form

powder

Mol-Gew.

Mw 205.64 g/mol

Methode(n)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

Farbe

white to off-white

mp (Schmelzpunkt)

214-215 °C (lit.)

Löslichkeit

water: soluble 50 mg/mL, clear, colorless to faintly yellow

Anwendung(en)

agriculture

SMILES String

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChIKey

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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Allgemeine Beschreibung

Pyridoxine is a water-soluble vitamin that exists in six forms called, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate, and pyridoxal 5′-phosphate. 

Anwendung

Pyridoxine hydrochloride has been used:
  • as a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies
  • as a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA
  • as a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity

Biochem./physiol. Wirkung

Pyridoxine functions as an essential coenzyme for amino acid, carbohydrate, and lipid metabolism. Pyridoxine deficiency is associated with peripheral neuropathy, microcytic anemia, and electroencephalographic abnormalities. It is implicated in a wide range of biochemical reactions that affect cellular processes. Pyridoxine serves as an alternative to pyridoxal which can degrade in media.

Piktogramme

Corrosion
GHS05

Signalwort

Danger

H-Sätze

H318

Gefahreneinstufungen

Eye Dam. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Carmela Vigorito et al.
International journal of molecular sciences, 20(9) (2019-05-11)
(1) The beneficial effects of hydrogen sulfide (H2S) on the cardiovascular and nervous system have recently been re-evaluated. It has been shown that lanthionine, a side product of H2S biosynthesis, previously used as a marker for H2S production, is dramatically
Wanliang Shi
Antibiotics (Basel, Switzerland), 10(8) (2021-08-28)
Susceptibility testing of tuberculosis (TB) drugs on Mycobacterium tuberculosis is essential for the rapid detection of strains resistant to the drugs, providing the patient with effective treatment, and preventing the spread of drug-resistant TB strains. Pyrazinamide (PZA) is one of
Imène Mensi et al.
Bio-protocol, 7(2), e2111-e2111 (2017-01-20)
Sugarcane (interspecific hybrids of Saccharum species) is an economically important crop that provides 70% of raw table sugar production worldwide and contributes, in some countries, to bioethanol and electricity production. Leaf scald, caused by the bacterial plant pathogen Xanthomonas albilineans
N Milne et al.
FEMS yeast research, 20(2) (2019-09-27)
We present a teaching protocol suitable for demonstrating the use of EasyClone and CRISPR/Cas9 for metabolic engineering of industrially relevant yeasts Saccharomyces cerevisiae and Yarrowia lipolytica, using β-carotene production as a case study. The protocol details all steps required to
Vijay P Singh et al.
The Journal of organic chemistry, 78(4), 1478-1487 (2013-01-16)
Vitamin B6 is involved in a variety of enzymatic transformations. Some recent findings also indicate an antioxidant role of the vitamin in biological systems. We set out to turn pyridoxine (1a) into a catalytic chain-breaking and hydroperoxide-decomposing antioxidant by replacing
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Artikel

Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

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