This is a product of the European Pharmacopoeia.
Please see the link below for additional product information, including the Certificate (Leaflet):
https://crs.edqm.eu/db/4DCGI/View=N1300000
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Wichtige Dokumente
N1300000
Noscapin
European Pharmacopoeia (EP) Reference Standard
Synonym(e):
(S,R)-Noscapin
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About This Item
Empirische Formel (Hill-System):
C22H23NO7
CAS-Nummer:
Molekulargewicht:
413.42
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Empfohlene Produkte
Qualität
pharmaceutical primary standard
API-Familie
noscapine
Hersteller/Markenname
EDQM
mp (Schmelzpunkt)
174-176 °C (lit.)
Anwendung(en)
pharmaceutical (small molecule)
Format
neat
Lagertemp.
2-8°C
SMILES String
COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34
InChI
1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3/t17-,18+/m1/s1
InChIKey
AKNNEGZIBPJZJG-MSOLQXFVSA-N
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Allgemeine Beschreibung
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Anwendung
Noscapine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Verpackung
Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.
Sonstige Hinweise
Sales restrictions may apply.
Ähnliches Produkt
Produkt-Nr.
Beschreibung
Preisangaben
Signalwort
Warning
H-Sätze
P-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral - STOT SE 3
Zielorgane
Central nervous system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Hier finden Sie alle aktuellen Versionen:
Analysenzertifikate (COA)
Lot/Batch Number
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Ramesh Chandra et al.
Current drug metabolism, 13(10), 1476-1483 (2012-05-11)
Noscapine, a tubulin binding anticancer agent undergoing Phase I/II clinical trials, inhibits tumor growth in nude mice bearing human xenografts of breast, lung, ovarian, brain, and prostrate origin. The analogues of noscapine like 9-bromonoscapine (EM011) are 5 to 10-fold more
Harpal Singh et al.
Current drug metabolism, 14(3), 351-360 (2012-09-01)
This review introduces the Noscapine, which is being used as an antitussive drug for a long time has been recently discovered as a novel tubulin-binding, anti-angiogenic anticancer drug that causes cell cycle arrest and induces apoptosis in cancer cells both
Melissa M Gajewski et al.
Pharmaceutical research, 29(11), 2985-2993 (2012-06-27)
This article reviews the recent findings regarding the binding sites, binding modes and binding affinities of three novel antimitotic drugs peloruside, laulimalide and noscapine with respect to tubulin as the target of their action. These natural compounds are shown to
Massoud Mahmoudian et al.
Recent patents on anti-cancer drug discovery, 4(1), 92-97 (2009-01-20)
Noscapine is an isoqiunoline alkaloid found in opium latex. Unlike most other alkaloids obtained from opium latex, noscapine is not sedative and has been used as antitussive drug in various countries. Recently, it has been introduced as an anti-mitotic agent.
Noscapine may increase the effect of warfarin.
Staffan Ohlsson et al.
British journal of clinical pharmacology, 65(2), 277-278 (2007-09-19)
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I am looking for a Certificate of Analysis for Noscapine, N1300000. There doesn't appear to be one on your website
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