F6145

Fenspirid -hydrochlorid

analytical standard, for drug analysis

• Synonym(e): 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-on -hydrochlorid
• Empirische Formel (Hill-System): C₁₅H₂₀N₂O₂ · HCl
• CAS-Nummer: 5053-08-7
• Molekulargewicht: 296.79
• EG-Nummer: 225-752-9
• MDL-Nummer: MFCD00133315
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329799751

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 200
• Assay: >99% (TLC)
• Form: powder
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Farbe: white
• Anwendung(en): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Format: neat
• SMILES String: Cl.O=C1NCC2(CCN(CCc3ccccc3)CC2)O1
• InChI: 1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13;/h1-5H,6-12H2,(H,16,18);1H
• InChIKey: FIKFLLIUPUVONI-UHFFFAOYSA-N
• Angaben zum Gen: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , HRH1(3269)

Beschreibung

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H₁ histamine receptors.
Fenspiride hydrochloride possesses anti-allergic and anti-bronchoconstrictive properties. It is used as a drug to treat inflammatory conditions of the upper and lower respiratory tracts. Experimental studies state that fenspiride has an ability to reduce the development of myringosclerosis, possibly by restricting the formation of oxygen-derived free radicals.

Bronchospasmolytikum mit enzündungshemmender Wirkung. Inhibiert die Schleimsekretion und verringert die Freisetzung von Tachykininen (Neurokininen) durch seine antimuskarinische Wirkung auf einem prejunktionalen Level. Es ist möglicherweise auch ein Antagonist von a Adrenozeptoren und H₁ Histaminrezeptoren.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves