Acta poloniae pharmaceutica, 53(3), 167-169 (1996-05-01)
A local anaesthetics diperodon by the action of hydrolazes in blood serum is decomposed. A method for its determination in blood serum in vitro has been worked out. It was found that during the first 2 hours it decomposes rather
Journal of pharmaceutical and biomedical analysis, 30(3), 875-880 (2002-10-09)
An on-line coupled HPLC system is described for the determination of the enantiomers of diperodon in blood serum. The method involves three steps: (i) off-line preconcentration and clean-up, (ii) separation of the diperodon enantiomers from the matrix components on a
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 53(5), 225-227 (2004-10-28)
The chiral stationary phase on the base of teicoplanin and the polar-organic mobile phase methanol/acetonitrile/acetic acid/triethylamine 45/55/0.3/0.2 was used for the separation of diperodon enantiomers. The developed method was suitable to determine the enantiomers in blood serum up to 0.5
We explored the potential for autophagy to regulate budding yeast meiosis. Following pre-meiotic DNA replication, we blocked autophagy by chemical inhibition of Atg1 kinase or engineered degradation of Atg14 and observed homologous chromosome segregation followed by sister chromatid separation; cells
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