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BCR265

Dibenzo[a,e]fluoranthen

BCR®, certified reference material

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About This Item

Empirische Formel (Hill-System):
C24H14
CAS-Nummer:
Molekulargewicht:
302.37
Beilstein:
2120920
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material

Agentur

BCR®

Hersteller/Markenname

JRC

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Format

neat

Lagertemp.

2-8°C

SMILES String

c1ccc-2c(c1)-c3cc4ccccc4c5cc6ccccc6c-2c35

InChI

1S/C24H14/c1-3-9-17-15(7-1)13-22-19-11-5-6-12-20(19)23-18-10-4-2-8-16(18)14-21(17)24(22)23/h1-14H

InChIKey

JHOWUOKQHJHGMU-UHFFFAOYSA-N

Hinweis zur Analyse

For more information please see:
BCR265

Rechtliche Hinweise

BCR is a registered trademark of European Commission

Piktogramme

Health hazard

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Carc. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Metabolic activation of dibenzo(a,e)fluoranthene, a nonalternant carcinogenic polycyclic hydrocarbon, in liver homogenates.
O Perin-Roussel et al.
Cancer research, 40(5), 1742-1749 (1980-05-01)
F Zajdela et al.
Carcinogenesis, 8(3), 461-464 (1987-03-01)
Dibenzofluoranthene-12,13-dihydrodiol (DBF-12,13-DHD) is six times more mutagenic in Salmonella TA100 than dibenzofluoranthene-3,4-dihydrodiol (DBF-3,4-DHD). However, these two major dibenzo[a,e]fluoranthene (DBF) proximate metabolites, which are immediate precursors of the corresponding diolepoxides, showed on an equimolar basis nearly identical initiation activities on mouse
O Perin-Roussel et al.
Cancer letters, 36(2), 169-180 (1987-08-01)
The production by dibenzo[a,e]fluoranthene (DBF) of DNA-protein cross-links in cultured mouse fibroblasts is probably mediated by the activation of proximate metabolites of DBF and not by the DBF molecule itself. In order to test this hypothesis, several agents that enhance
S Saguem et al.
Carcinogenesis, 4(7), 827-835 (1983-01-01)
The metabolism of the polycyclic hydrocarbon dibenzo[a,e]fluoranthene (DBF) has been investigated. Two new primary metabolites have been identified by proton n.m.r. as the trans diaxial dihydrodiols of the bay and of the pseudo bay regions of DBF. In addition, twelve
O Périn-Roussel et al.
Carcinogenesis, 9(8), 1383-1388 (1988-08-01)
The three-dimensional distribution of nuclear DNA damage induced by dibenzo(a,e)fluoranthene (DBF), a potent carcinogen for mouse fibroblasts, has been examined. The intact supercoiled nuclear DNA obtained from nucleoids of mouse fibroblasts incubated with DBF was fractionated into loop DNA attached

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