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BCR081R

5-Methyl-chrysen

BCR®, certified reference material

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About This Item

Empirische Formel (Hill-System):
C19H14
CAS-Nummer:
3697-24-3
Molekulargewicht:
242.31
Beilstein:
2048519
MDL-Nummer:
MFCD00215919
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329774213

Qualität

certified reference material

Agentur

BCR®

Hersteller/Markenname

JRC

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

environmental
pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Cc1cc2ccccc2c3ccc4ccccc4c13

InChI

1S/C19H14/c1-13-12-15-7-3-4-8-16(15)18-11-10-14-6-2-5-9-17(14)19(13)18/h2-12H,1H3

InChIKey

GOHBXWHNJHENRX-UHFFFAOYSA-N

Hinweis zur Analyse

For more information please see:
BCR080R

Rechtliche Hinweise

BCR is a registered trademark of European Commission

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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T Kuljukka-Rabb et al.
Mutagenesis, 16(4), 353-358 (2001-06-23)
Cultures of a human mammary carcinoma cell line (MCF-7) were exposed to the soluble organic fraction of diesel particle emissions, benzo[a]pyrene (B[a]P) and 5-methylchrysene (5-MeCHR) to study time- and dose-related PAH-DNA binding. The concentrations of 14 PAHs in three extracts
C A Bigger et al.
Carcinogenesis, 11(12), 2263-2265 (1990-12-01)
An SV40-based pS189 shuttle vector, which contained a supF target gene and was replicated in human cells (Ad293), was used to determine the mutational specificity of anti 5-methylchrysene 1,2-dihydrodiol 3,4-epoxide, the active metabolite of the environmentally prevalent carcinogen 5-methylchrysene. The
Stephen S Hecht et al.
Cancer letters, 187(1-2), 87-94 (2002-10-03)
Polycyclic aromatic hydrocarbons (PAH) are an important group of carcinogens that are likely to be involved as one of the causes of lung cancer in smokers and occupationally exposed individuals. Previous studies have shown that benzyl isothiocyanate (BITC), administered by
S Amin et al.
Chemical research in toxicology, 5(2), 237-241 (1992-03-01)
In previous studies, we have observed unexpected structure-tumorigenicity relationships among the dimethylchrysenes. Thus, 5,6-dimethylchrysene and 5,7-dimethylchrysene were only weakly tumorigenic and were significantly less active than 5-methylchrysene. These results were surprising in view of the known route of metabolic activation
D B Reardon et al.
Carcinogenesis, 8(9), 1317-1322 (1987-09-01)
Products of reaction of the racemic anti bay region 1,2-dihydrodiol-3,4-epoxide of 5-methylchrysene with DNA were identified by comparison with the products formed in reactions with individual nucleotides. The latter products, i.e. two deoxyguanosine adducts and four deoxyadenosine adducts, were characterized
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