63177

6-Maleinimido-capronsäure-N-succinimidylester

≥98.0% (HPLC)

• Synonym(e): N-(ε-Maleinimidocaproyloxy)-succinimid, N-Succinimidyl-6-maleinimido-caproat, EMCS
• Empirische Formel (Hill-System): C₁₄H₁₆N₂O₆
• CAS-Nummer: 55750-63-5
• Molekulargewicht: 308.29
• Beilstein: 1499815
• MDL-Nummer: MFCD00043043
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 329759804
• NACRES: NA.25

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98.0% (HPLC)
• Form: solid
• Eignung der Reaktion: reagent type: linker
• mp (Schmelzpunkt): 67-73 °C; 70-73 °C (lit.)
• Funktionelle Gruppe: NHS ester
• Lagertemp.: −20°C
• SMILES String: O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
• InChI: 1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
• InChIKey: VLARLSIGSPVYHX-UHFFFAOYSA-N

Beschreibung

Anwendung

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Reagent for cross-linking and immobilisation of proteins

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves