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03395

Sigma-Aldrich

Poly(ethylenglykol)

tested according to Ph. Eur., 1,000

Synonym(e):

Macrogolum 1′000, PEG

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About This Item

Lineare Formel:
H(OCH2CH2)nOH
CAS-Nummer:
25322-68-3
MDL-Nummer:
MFCD00081839
UNSPSC-Code:
12352104
PubChem Substanz-ID:
24845476
NACRES:
NA.21

Agentur

tested according to Ph. Eur.

Qualitätsniveau

100

Form

waxy solid

Mol-Gew.

950-1050

Löslichkeit

aliphatic hydrocarbons: slightly soluble
organic solvents: soluble

Anwendung(en)

pharmaceutical (small molecule)

SMILES String

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChIKey

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Anwendung

Poly(ethylene glycol) is a chemical fusogen, which mediates the premature chromosome condensation induction in human and rat lymphocytes as well as in rodent spleen cells, and spleen and whole body cells of newborn mice.[1]

Biochem./physiol. Wirkung

Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.[2][3]

Angaben zur Herstellung

Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

281.5 °F - closed cup

Flammpunkt (°C)

138.6 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCJ0189
BCCG5630
BCCF8555
BCCD9463
BCCB4833

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Sigma-Aldrich

86101

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Sigma-Aldrich

81242

Poly(ethylenglykol)

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Sigma-Aldrich

295906

Poly(ethylenglykol)

G E Pantelias et al.
Somatic cell genetics, 9(5), 533-547 (1983-09-01)
Even though polyethylene glycol (PEG) has been shown to be a potent fusogen, it has not been widely exploited as an alternative to the Sendai virus for premature chromosome condensation (PCC) induction. A simple, rapid, and reproducible PEG protocol for
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
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