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01580590

Ginsenosid Rf

primary reference standard

Synonym(e):

(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid, Panaxosid Rf

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About This Item

Empirische Formel (Hill-System):
C42H72O14
CAS-Nummer:
Molekulargewicht:
801.01
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

483,00 €


Versandbereit am17. April 2025Details


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Qualität

primary reference standard

Haltbarkeit

limited shelf life, expiry date on the label

Hersteller/Markenname

HWI

Anwendung(en)

food and beverages

Lagertemp.

−20°C

SMILES String

[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]2([H])O[C@H]3C[C@]4(C)[C@]([H])(C[C@@H](O)[C@]5([H])[C@]([H])(CC[C@@]45C)[C@@](C)(O)CC\C=C(/C)C)[C@@]6(C)CC[C@H](O)C(C)(C)[C@]36[H]

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,39+,40+,41+,42-/m0/s1

InChIKey

UZIOUZHBUYLDHW-XUBRWZAZSA-N

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Allgemeine Beschreibung

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng.[1] Ginsenoside Rf, a variety of ginseng saponins with attached sugars moieties which inhibits the Ca2+ channels present in primary sensory neurons.[2]
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Anwendung

It may be used as reference standard in HPLC-MS/MS analysis of human plasma to determine Ginsenosides from herbal products containing Panax ginseng and Panax quinquefolius.[3]

Sonstige Hinweise

This compound is commonly found in plants of the genus: panax

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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1 of 4

Cuk-seong Kim et al.
Acta pharmacologica Sinica, 26(5), 551-558 (2005-04-22)
To examine the effects of ginseng saponins on the heterologously expressed human ether-a-go-go related gene (HERG) that encodes the rapid component of the delayed rectifier K+ channel. A two-electrode voltage clamp technique was used. HERG currents were recorded in Xenopus
Sunoh Kim et al.
Biochemical and biophysical research communications, 365(3), 399-405 (2007-11-21)
In the present study, we have examined any possible involvement of L-type Ca(2+) channels in ginseng-mediated neuroprotective actions. Exposure to a 50mM KCl (high-K) produced neuronal cell death, which was blocked by a selective L-type Ca(2+) channel blocker in cultured
Noel S Quiming et al.
Analytical and bioanalytical chemistry, 389(5), 1477-1488 (2007-09-07)
The influences of the organic component of the mobile phase and the column temperature on the retention of ginsenosides on a poly(vinyl alcohol) (PVA) bonded stationary phase operated under hydrophilic interaction chromatographic mode were investigated. The retention of the ginsenosides
The antimetastatic and immunomodulating activities of ginseng minor glycosides.
A M Popov et al.
Doklady. Biochemistry and biophysics, 380, 309-312 (2001-12-01)
Chang-Chun Ruan et al.
Molecules (Basel, Switzerland), 14(6), 2043-2048 (2009-06-11)
An Aspergillus niger strain was isolated from the soil around ginseng fruit. In vitro enzyme assays showed that this strain had the ability to transform total ginsenosides (TGS) into several new products. In a further biochemical study, a beta-glucosidase gene

Artikel

Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.

In this article we present several HPTLC applications and analytical standards for ginsenosides.

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