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Merck

MTH17MAG-47K

Millipore

MILLIPLEX® Mouse TH17 Magnetic Bead Panel - Immunology Multiplex Assay

Simultaneously analyze multiple Th17 cytokine and chemokine biomarkers with the Th17 Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

Synonym(e):

Luminex® Mouse Immunology Panel, Millipore Mouse Immunology Panel, Mouse Immunology Protein Multiplex Assay

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84

To order a Milliplex® kit, please search for your analyte of interest.

Qualitätsniveau

Speziesreaktivität

mouse

Hersteller/Markenname

Milliplex®

assay range

linearity: 111.0%
(1:04)

linearity: 113.1%
(1:08)

standard curve range: 1.5-1,500 pg/mL
(IL-4)

standard curve range: 10-10,000 pg/mL
(IL-17F)

standard curve range: 127-130,000 pg/mL
(IL-28B)

standard curve range: 15-15,000 pg/mL
(IL-1β)

standard curve range: 2.4-2,500 pg/mL
(IL-22)

standard curve range: 20-20,000 pg/mL
(IL-10, IL-12(p70), & IL-21)

standard curve range: 3.4-3,500 pg/mL
(TNFα)

standard curve range: 34-35,000 pg/mL
(GM-CSF & IL-15)

standard curve range: 342-350,000 pg/mL
(IL-23)

standard curve range: 39-40,000 pg/mL
(IL-13 & IL-17A)

standard curve range: 4.9-5,000 pg/mL
(IL-5)

standard curve range: 488-500,000 pg/mL
(TNFβ)

standard curve range: 49-50,000 pg/mL
(CD40L IL-31 & MIP-3α)

standard curve range: 586-600,000 pg/mL
(IL-17E/ IL-25)

standard curve range: 6.9-6,000 pg/mL
(IL-2)

standard curve range: 7.8-8,000 pg/mL
(IFNγ & IL-6)

standard curve range: 78-80,000 pg/mL
(IL-33)

standard curve range: 879-900,000 pg/mL
(IL-27)

Methode(n)

multiplexing: suitable

Nachweisverfahren

fluorometric (Luminex xMAP)

Versandbedingung

wet ice

Allgemeine Beschreibung

The MILLIPLEX® Mouse Th17 Bead panel enables you to focus on the therapeutic potential of the modulation of CD4 T-helper cell cytokines. Coupled with the Luminex® xMAP®platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.

Panel Type: Cytokines/Chemokines

Spezifität

Cross Reactivty
There was no or minimum cross-reactivity between the antibodies and any other analytes in the panel (see details in assay protocol).

Anwendung

  • Analytes: CD40 Ligand, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27, IL-28B, IL-31, IL-33, MIP-3α/CCL20, TNF-α, TNFβ
  • Recommended Sample type: serum, plasma or tissue/cell lysate and culture supernatant
  • Recommended Sample dilution: neat
  • Assay Run Time: overnight or one day
  • Research Category: Inflammation & Immunology

Leistungsmerkmale und Vorteile

Design your multiplex kit by choosing available analytes within this panel.

Lagerung und Haltbarkeit

Recommended storage for kit components is 2 - 8°C.

Sonstige Hinweise

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

Rechtliche Hinweise

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Zielorgane

Respiratory Tract

Lagerklassenschlüssel

10 - Combustible liquids


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Mohammad Afzal Khan et al.
Frontiers in immunology, 9, 1010-1010 (2018-06-09)
Microvascular injury during acute rejection has been associated with massive infiltration of CD4+ T effector cells, and the formation of complement products (C3a and C5a). Regulatory T cells (Tregs) are potent immunosuppressors of the adaptive immune system and have proven
M John Albert et al.
Scientific reports, 9(1), 12024-12024 (2019-08-21)
There is no information on cytokine profiles for use as markers of protection in Campylobacter jejuni infection. To study this, we used outer membrane protein (MOMP [PorA]) as the vaccine for protection and spleen cell cytokines as markers of protection.
Mohammad Afzal Khan et al.
Cells, 10(5) (2021-06-03)
Interleukin-10 plays a vital role in maintaining peripheral immunotolerance and favors a regulatory immune milieu through the suppression of T effector cells. Inflammation-induced microvascular loss has been associated with airway epithelial injury, which is a key pathological source of graft
Sarah J Dulson et al.
Journal of immunology (Baltimore, Md. : 1950), 203(9), 2472-2484 (2019-09-29)
Innate lymphoid cells (ILCs) are strategically positioned at mucosal barrier surfaces where they respond quickly to infection or injury. Therefore, we hypothesized that ILCs are key contributors to the early immune response in the intestine against Listeria monocytogenes Using a
Martín Ignacio González-Rodríguez et al.
Immunity, inflammation and disease, 10(3), e579-e579 (2021-12-08)
The hygiene hypothesis suggests that decrease in early life infections due to increased societal-level hygiene standards subjects one to allergic and autoimmune diseases. In this report, we have studied the effect of sterilized forest soil and plant-based material on mouse

Verwandter Inhalt

See how multiplexing the inflammation signaling pathway with MILLIPLEX® inflammation assays or cell signaling assays can help researchers bridge the gap between immunology and cell signaling, including investigating T cell signaling, Th Cell differentiation, inflammatory response signaling, and sepsis signaling.

Discover the benefits of MILLIPLEX® multiplex assays, based on Luminex® xMAP® multiplex assay technology, that provide consistent, high-quality results and see how these multiplex biomarker Luminex® assays are being used to advance research.

Fragen

  1. Can you provide information on the cross-reactivity of the MIP-3a/CCL20 from the Mouse TH17 kit with Rat?

    1 Antwort
    1. The Mouse MIP-3a capture was tested against recombinant rat MIP-3a and did not show any reactivity. Therefore, the Mouse MIP-3a cannot be recommended for rat samples.

      Hilfreich?

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