MAB3502-I

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2

culture supernatant, clone 2E2, from mouse

• Synonym(e): Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II, CD143
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: 2E2, monoclonal
• Speziesreaktivität: rat
• Speziesreaktivität (Voraussage durch Homologie): human (immunogen homology)
• Methode(n): western blot: suitable
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NP_000780
• UniProt-Hinterlegungsnummer: P12821
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ACE(1636)

Beschreibung

Allgemeine Beschreibung

Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.

Immunogen

Human Angiotensin Converting Enzyme.

Anwendung

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.

Qualität

Evaluated by Western Blot in rat Angiotensin Converting Enzyme.

Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.

Zielbeschreibung

~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.

Verlinkung

Replaces: MAB3502

Physikalische Form

Mouse monoclonal IgG1 cultured supernatant without preservatives.

Hinweis zur Analyse

Control
Rat Angiotensin Converting Enzyme

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable