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FCMAB198F

Sigma-Aldrich

Milli-Mark® Anti-CD54-FITC Antibody, clone 6.5B5

clone 6.5B5, Milli-Mark®, from mouse

Synonym(e):

Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.44

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

FITC conjugate

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

6.5B5, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Milli-Mark®

Methode(n)

flow cytometry: suitable

Isotyp

IgG1κ

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ICAM1(3383)

Allgemeine Beschreibung

The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family. The ligand for ICAM-1 is LFA-1 (leucocyte function associated-1 protein) (Berendt, 1992). ICAM-1 is widely expressed on many cell types, although the degree of expression by unstimulated resting cells varies. As a cellular activation antigen the expression of ICAM-1 is up-regulated upon cell activation, being induced particularly in response to cytokines such as interleukin-1, tumor necrosis factor, and interferon- (Berendt, 1992; Wellicome, 1990; Thornhill, 1990). ICAM-1 might be a receptor for rhinovirus (Staunton, 1989). In rejecting kidneys the antibody stains all infiltrating cells strongly as well as glomerulus epithelium, endothelium on capillaries, large vessels, and mesangium (Waugh, 1989).

Spezifität

Antibody recognizes Human CD54 antigen.

Immunogen

TNF-activated human umbilical vein endothelial cells

Anwendung

Research Category
Entzündung & Immunologie
Research Sub Category
Immunoglobuline & Immunologie
Milli-Mark Anti-CD54-FITC Antibody, clone 6.5B5 is an antibody against CD54 for use in FC.

Qualität

Evaluated by flow cytometry using human lymphocytes

Zielbeschreibung

90 kDa (Springer, 1990)

Physikalische Form

Protein A purified
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Lagerung und Haltbarkeit

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Hinweis zur Analyse

Control
Human Lymphocytes

Rechtliche Hinweise

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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