Direkt zum Inhalt
Merck
Alle Fotos(2)

Wichtige Dokumente

ABN363

Sigma-Aldrich

Anti-Myelin Protein P0 Antibody

from rabbit, purified by affinity chromatography

Synonym(e):

Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Größe auswählen

100 μL
445,00 €

445,00 €


Voraussichtliches Versanddatum10. April 2025


Bulk-Bestellung anfordern

Größe auswählen

Ansicht ändern
100 μL
445,00 €

About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

445,00 €


Voraussichtliches Versanddatum10. April 2025


Bulk-Bestellung anfordern

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

rat, mouse

Speziesreaktivität (Voraussage durch Homologie)

bovine (based on 100% sequence homology), horse (based on 100% sequence homology), human (based on 100% sequence homology)

Methode(n)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... MPZ(4359)

Allgemeine Beschreibung

Myelin protein P0 is also called Myelin peripheral protein (MPP) and Myelin protein zero (MPZ). Myelin protein P0 is found only in peripheral nervous system and is involved in the creation of an extracellular membrane face which guides the wrapping process that eventually leads to the compaction of adjacent lamellae. Myelin protein P0 is related to several disease states including Charcot-Marie-Tooth disease 1B (CMT1B), Charcot-Marie-Tooth disease 2I (CMT2I), Charcot-Marie-Tooth disease 2J (CMT2J), Adie pupil (ADIEP), Charcot-Marie-Tooth disease, dominant, intermediate type, D (CMTDID), Dejerine-Sottas syndrome (DSS), Congenital hypomyelination neuropathy (CHN), and Roussy-Levy syndrome (ROULS).

Immunogen

KLH-conjugated linear peptide corresponding to the extracellular domain of human Myelin protein P0.

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Entwicklungsneurowissenschaft
Anti-Myelin Protein P0 Antibody is a highly specific rabbit polyclonal antibody, that targets Myelin Protein & has been tested in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Myelin protein P0 in rat spinal cord sections.

Qualität

Evaluated by Western Blotting in rat spinal cord tissue lysate.

Western Blotting Analysis: A 1:5,000 dilution of this antibody detected Myelin protein P0 in 10 µg of rat spinal cord tissue lysate.

Zielbeschreibung

~30 kDa observed

Physikalische Form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sie haben nicht das passende Produkt gefunden?  

Probieren Sie unser Produkt-Auswahlhilfe. aus.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Ying Zou et al.
Cell & bioscience, 11(1), 210-210 (2021-12-16)
Silent information regulator 6 (SIRT6) is a mammalian homolog of the nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin family. Prior evidences suggested that the anti-inflammatory function of SIRT6 after spinal cord and brain injury, and it plays a crucial role in
Ramazan Üstün et al.
Experimental and therapeutic medicine, 28(3), 345-345 (2024-07-29)
Traumatic and postoperative hemorrhages are life-threatening complications. Ankaferd BloodStopper (ABS) is a potent topical hemostatic agent to stop bleeding. However, ABS is associated with nerve toxicity. The present study aimed to investigate the functional and structural neurodegenerative effects of ABS
Sandra Murphy et al.
Journal of proteomics, 191, 212-227 (2018-02-07)
The highly progressive neuromuscular disorder dystrophinopathy is triggered by primary abnormalities in the Dmd gene, which causes cytoskeletal instability and loss of sarcolemmal integrity. Comparative organellar proteomics was employed to identify sarcolemma-associated proteins with an altered concentration in dystrophic muscle
Yan Guo et al.
Signal transduction and targeted therapy, 9(1), 32-32 (2024-02-14)
The appropriate and specific response of nerve cells to various external cues is essential for the establishment and maintenance of neural circuits, and this process requires the proper recruitment of adaptor molecules to selectively activate downstream pathways. Here, we identified
Jiawei Xu et al.
Journal of neuroinflammation, 18(1), 234-234 (2021-10-17)
Plenty of macrophages are recruited to the injured nerve to play key roles in the immunoreaction and engulf the debris of degenerated axons and myelin during Wallerian degeneration, thus creating a conducive microenvironment for nerve regeneration. Recently, drugs targeting the

Fragen

Bewertungen

Kein Beurteilungswert

Aktive Filter

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.