197225

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control

A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.

• Synonym(e): Bcl-2 Binding Peptide, Cell-Permeable, Negative Control, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH, cpm-1285m, cpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
• Empirische Formel (Hill-System): C₁₅₀H₂₃₄N₄₄O₄₂S
• Molekulargewicht: 3357.80
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated (hygroscopic)
• Farbe: off-white
• Löslichkeit: DMSO: 10 mg/mL
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Suitable for use as a negative control for Cat. No. 197220.

Biochem./physiol. Wirkung

Cell permeable: yes

Primary Target
A negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).

Product does not compete with ATP.

Reversible: no

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Standard Handling (A)

Sequenz

CH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH

Physikalische Form

Supplied as a trifluoroacetate salt.

Rekonstituierung

Following reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.

Sonstige Hinweise

Wang, J-L., et al. 2000. Cancer Res.60, 1498.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable