14-1048
Human recombinant CARM1
Human recombinant CARM1 with an N-terminal FLAG tag expressed in FreeStyle 293-F cells.
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About This Item
UNSPSC-Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Rekombinant
expressed in FreeStyle™ 293-F cells
Qualitätsniveau
Mol-Gew.
Mw ~66 kDa
Hersteller/Markenname
Upstate®
Methode(n)
activity assay: suitable (histone methyltransferase (HMT))
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Angaben zum Gen
human ... CARM1(10498)
Allgemeine Beschreibung
Product Source: Human
Anwendung
Human recombinant CARM1 with an N-terminal FLAG tag expressed in FreeStyle 293-F cells.
Research Category
Nuclear Function
Nuclear Function
Qualität
routinely evaluated by methylation of histone H3
Verlinkung
Replaces: 14-575
Lagerung und Haltbarkeit
6 months at -80°C.
Sonstige Hinweise
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Varies by lot; see lot-specific datasheet for information on each lot.
Rechtliche Hinweise
FreeStyle is a trademark of Invitrogen Corp.
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Seth Frietze et al.
Cancer research, 68(1), 301-306 (2008-01-04)
Estrogen receptor alpha (ER alpha) mediates breast cancer proliferation through transcriptional mechanisms involving the recruitment of specific coregulator complexes to the promoters of cell cycle genes. The coactivator-associated arginine methyltransferase CARM1 is a positive regulator of ER alpha-mediated transcriptional activation.
Melody D Fulton et al.
The Journal of biological chemistry, 297(4), 101123-101123 (2021-09-08)
Histone arginine methylation is a key post-translational modification that mediates epigenetic events that activate or repress gene transcription. Protein arginine methyltransferases (PRMTs) are the driving force for the process of arginine methylation, and the core histone proteins have been shown
Hongwei Li et al.
The Journal of biological chemistry, 277(47), 44623-44630 (2002-09-19)
The RNA-binding protein HuR stabilizes labile mRNAs carrying AU-rich instability elements. This mRNA stabilization can be induced by hypoxia, lipopolysaccharide, and UV light. The mechanism by which these stimuli activate HuR is unclear and might be related to post-translational modification
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