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Sigma-Aldrich

CHKtide (CHK1/CHK2 substrate peptide)

CHKtide (CHK1/CHK2 substrate peptide) primarily used in Kinase Assays.

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About This Item

UNSPSC-Code:
12352200
eCl@ss:
32160405
NACRES:
NA.41

Qualitätsniveau

Hersteller/Markenname

Upstate®

Methode(n)

activity assay: suitable (kinase)

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Angaben zum Gen

human ... CHEK1(1111)

Biochem./physiol. Wirkung

Protein Target: CHK
Target Sub-Family: CAMK

Qualität

Routinely evaluated by Protein Kinase Assay as a substrate for the active CHK1 (Catalog #14-346) and CHK2 (Catalog #14-347) kinases.

Physikalische Form

Lyophilized powder

Lagerung und Haltbarkeit

Lyophilized: 2 years at 4°C; Rehydrated: 6 months at -20°C.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Hidemasa Oh et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(9), 5378-5383 (2003-04-19)
The "postmitotic" phenotype in adult cardiac muscle exhibits similarities to replicative senescence more generally and constitutes a barrier to effective restorative growth in heart disease. Telomere dysfunction is implicated in senescence and apoptotic signaling but its potential role in heart
B Furnari et al.
Science (New York, N.Y.), 277(5331), 1495-1497 (1997-09-05)
Arrest of the cell cycle at the G2 checkpoint, induced by DNA damage, requires inhibitory phosphorylation of the kinase Cdc2 in both fission yeast and human cells. The kinase Wee1 and the phosphatase Cdc25, which regulate Cdc2 phosphorylation, were evaluated
Y Sanchez et al.
Science (New York, N.Y.), 277(5331), 1497-1501 (1997-09-05)
In response to DNA damage, mammalian cells prevent cell cycle progression through the control of critical cell cycle regulators. A human gene was identified that encodes the protein Chk1, a homolog of the Schizosaccharomyces pombe Chk1 protein kinase, which is

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