1.04119

Osmium(VIII) oxide

for microscopy

• Synonym(e): Osmium(VIII) oxide
• Empirische Formel (Hill-System): O₄Os
• CAS-Nummer: 20816-12-0
• Molekulargewicht: 254.23
• MDL-Nummer: MFCD00011150
• UNSPSC-Code: 12352303

Eigenschaften

• Dampfdruck: 10 hPa ( 20 °C)
• Qualitätsniveau: 200
• Wirksamkeit: 15 mg/kg LD₅₀, oral (Rat)
• Farbe: yellow
• pH-Wert: 6 (20 °C, 25 g/L in H₂O)
• bp: 130 °C/1013 hPa
• mp (Schmelzpunkt): 40 °C (decomposition)
• Löslichkeit: 65 g/L
• Dichte: 4.91 g/cm³ at 20 °C
• Schüttdichte: 1500 kg/m³
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: 15-25°C
• InChI: 1S/4O.Os
• InChIKey: VUVGYHUDAICLFK-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Osmium tetroxide for microscopy can be used to visualize unsaturated lipids. A part of the lipids is immediately blackened by the influence of osmic acid solution. The immediate black coloration results from the -C=C- double bond of the unsaturated fatty acid. The fatty acids that are made brownish at first can be blackened by treatment with 60-70% alcohol. For electron microscopy or semithin sectioning the glutardialdehyde-fixed specimens are post-fixed with osmium(VIII) oxide. Lipid inclusions appear black on a yellow to brown background.

Anwendung

for microscopy

Hinweis zur Analyse

Identity (Raman-spectrum): conforms

Sicherheitshinweise

• Piktogramme: GHS05,GHS06
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330 - H314
• P-Sätze: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable