KLH-conjugated, synthetic peptide corresponding to amino acids 46-62 (CKDDRLGQHVPTLHPTSE) of human Sar1 (a and b isoforms), with an N-terminal cysteine added for conjugation purposes
Anwendung
Research Category Zelluläre Signaltransduktion
Research Sub Category G-Proteine
Kinasen & Phosphatasen
Detect Sar1 using this Anti-Sar1 Antibody validated for use in WB.
Qualität
routinely evaluated by immunoblot on RIPA lysates from 3T3/A31 cells
Zielbeschreibung
Mr 21kDa
Physikalische Form
Protein A purified
Format: Purified
Lagerung und Haltbarkeit
stable 2 years at -20°C from date of shipment
Hinweis zur Analyse
Control Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Rechtliche Hinweise
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Dietary fat is an important source of nutrition. Here we identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption. The Sar1 family of proteins initiates the intracellular transport of proteins in COPII (coat protein)-coated
A structural view of the COPII vesicle coat.
Bickford, Lincoln C, et al.
Current Opinion in Structural Biology, 14, 147-153 (2004)
RNase H1-dependent, phosphorothioate-modified antisense oligonucleotides (PS-ASOs) can enter cells through endocytic pathways and need to be released from the membrane-enclosed organelles, a limiting step for antisense activity. Accumulating evidence has suggested that productive PS-ASO release mainly occurs from late endosomes
Phagosomes, by killing and degrading pathogens for antigen presentation, are organelles implicated in key aspects of innate and adaptive immunity. Although it has been well established that phagosomes consist of membranes from the plasma membrane, endosomes, and lysosomes, the notion
The intracellular transport of chylomicrons requires the small GTPase, Sar1b.
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
