GST fusion protein corresponding to residues 53-295 of rat MAGE-D1/NRAGE
Anwendung
Research Category Neurowissenschaft
Research Sub Category Neurodegenerative Krankheiten
Entwicklungsneurowissenschaft
Anti-MAGE-D1/NRAGE Antibody is an antibody against MAGE-D1/NRAGE for use in IP, WB, IH.
Qualität
routinely evaluated by immunoblot in RIPA lysates from PC12 cells
Zielbeschreibung
90-96 kDa
Physikalische Form
Antiserum
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, before the addition of glycerol to 30%
Lagerung und Haltbarkeit
2 years at -20°C
Rechtliche Hinweise
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 2
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The Journal of biological chemistry, 277(50), 48043-48050 (2002-10-12)
The p75 neurotrophin receptor (p75NTR) mediates signaling events leading to activation of the JNK pathway and cell death in a variety of cell types. We recently identified NRAGE, a protein that directly interacts with the p75NTR cytosolic region and facilitates
The mechanisms employed by the p75 neurotrophin receptor (p75NTR) to mediate neurotrophin-dependent apoptosis are poorly defined. Two-hybrid analyses were used to identify proteins involved in p75NTR apoptotic signaling, and a p75NTR binding partner termed NRAGE (for neurotrophin receptor-interacting MAGE homolog)
The melanoma antigen (MAGE) family consists of more than 60 genes, many of which are cancer-testis antigens that are highly expressed in cancer and play a critical role in tumorigenesis. However, the biochemical and cellular functions of this enigmatic family
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