07-1815
Anti-FIP200 Antibody
serum, from rabbit
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
serum
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Speziesreaktivität
human, rat, mouse
Methode(n)
western blot: suitable
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
rat ... Stx8(59074)
Allgemeine Beschreibung
Focal adhesion kinase family interacting protein of 200 kDa (FIP200) is a novel protein inhibitor for focal adhesion kinase (FAK). FIP200 inhibits kinase activity and associated cellular functions, such as cell adhesion, spreading, and motility in fibroblasts by binding directly to FAK.
Spezifität
This antibody recognizes the C-terminal region of FIP200.
Immunogen
Epitope: C-terminus
The immunogen was a synthetic peptide corresponding to the C-terminal region of FIP200.
Anwendung
Research Category
Zelluläre Signaltransduktion
Zelluläre Signaltransduktion
Research Sub Category
PI3K-, Akt-, & mTOR-Signalübertragung
PI3K-, Akt-, & mTOR-Signalübertragung
Detect FIP200 using this Anti-FIP200 Antibody validated for use in WB.
Qualität
Evaluated by western blot on HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect FIP200 in HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect FIP200 in HEK293 cell lysate.
Zielbeschreibung
200 kDa
Physikalische Form
Unpurified rabbit serum in buffer containing 0.05% sodium azide.
Lagerung und Haltbarkeit
Stable for 2 years at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
Analysenzertifikate (COA)
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Zhengwei Ma et al.
The Journal of clinical investigation, 130(9), 5011-5026 (2020-08-18)
Dysregulation of autophagy in diabetic kidney disease (DKD) has been reported, but the underlying mechanism and its pathogenic role remain elusive. We show that autophagy was inhibited in DKD models and in human diabetic kidneys. Ablation of autophagy-related gene 7
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