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850530O
Avanti
7.7 MAG
Avanti Research™ - A Croda Brand 850530O
Synonym(e):
1-(7Z-tetradecenoyl)-rac-glycerol
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Größe auswählen
200 MG
633,00 €
500 MG
1.360,00 €
1 G
2.410,00 €
Alle Fotos(2)
Größe auswählen
Ansicht ändern
200 MG
633,00 €
500 MG
1.360,00 €
1 G
2.410,00 €
About This Item
Empirische Formel (Hill-System):
C17H32O4
CAS-Nummer:
Molekulargewicht:
300.43
MDL-Nummer:
UNSPSC-Code:
12352211
NACRES:
NA.25
Empfohlene Produkte
Assay
>99% (TLC)
Form
oil
Mol-Gew.
300.43 g/mol
Verpackung
pkg of 10 × 0.1 g (with screw cap (850530O-1g))
pkg of 2 × 100 mg (with screw cap (850530O-200mg))
pkg of 5 × 100 mg (with screw cap (850530O-500mg))
Hersteller/Markenname
Avanti Research™ - A Croda Brand 850530O
Methode(n)
protein sequencing: suitable
Versandbedingung
dry ice
Lagertemp.
−20°C
Allgemeine Beschreibung
Monoacylglycerols (MAGs) are glycerol esters.[1] 7.7 MAG has a 14 carbon acyl chain[2] and possess a bilayer thickness of 25.8 Å.[3]
This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.
Anwendung
7.7 MAG may be used as a host lipid in MdfA (multidrug transporter protein)–YN1074 (Fab fragment) complex for crystallization by lipidic cubic phase (LCP) method.[4]
Biochem./physiol. Wirkung
Monoacylglycerols (MAGs) are used in food industry as emulsifiers.[1] 7.7 MAG participates in meso crystallization of BtuB (vitamin B12 transporter), an outer membrane protein. It can also help in lysozyme crystal growth. 7.7 MAG also plays a key role in the growth of diffraction-quality crystals.[5] MAGs holds high significance in pharmaceutical and food industry.[6]
Verpackung
5 mL PTFE Vial with Screw Cap (850530O-1g)
5 mL PTFE Vial with Screw Cap (850530O-200mg)
5 mL PTFE Vial with Screw Cap (850530O-500mg)
Rechtliche Hinweise
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Lagerklassenschlüssel
11 - Combustible Solids
Hier finden Sie alle aktuellen Versionen:
Analysenzertifikate (COA)
Lot/Batch Number
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Kai Yu Chen et al.
Journal of agricultural and food chemistry, 67(29), 8191-8196 (2019-07-10)
Conversion of free fatty acids into monoacylglycerol gives rise to new structural properties, particularly amphipathic property. Therefore, monoacylglycerols are widely used in pharmaceutical and food industries and are also reported to facilitate better absorption into the human body. A functional
Protein
Johner N, et al.
Journal of the American Chemical Society, 136, 3271-3271 (2014)
Lisa V Misquitta et al.
Structure (London, England : 1993), 12(12), 2113-2124 (2004-12-04)
Monoacylglycerols have been used as bilayered hosts for growing crystals of membrane proteins. To date, the lipids used have had chains 16 and 18 carbon atoms long. We hypothesized that a shorter-chained lipid producing a thinner bilayer would facilitate the
Kumar Nagarathinam et al.
Acta crystallographica. Section F, Structural biology communications, 73(Pt 7), 423-430 (2017-07-12)
The active efflux of antibiotics by multidrug-resistance (MDR) transporters is a major pathway of drug resistance and complicates the clinical treatment of bacterial infections. MdfA is a member of the major facilitator superfamily (MFS) from Escherichia coli and provides resistance
Dianfan Li et al.
Crystal growth & design, 11(2), 530-537 (2011-07-12)
The default lipid for the bulk of the crystallogenesis studies performed to date using the cubic mesophase method is monoolein. There is no good reason however, why this 18-carbon, cis-monounsaturated monoacylglycerol should be the preferred lipid for all target membrane
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