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810606P

Avanti

16:0 Tempo PC

Avanti Research - A Croda Brand 810606P, powder

Synonym(e):

1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline

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About This Item

Empirische Formel (Hill-System):
C48H94N2O9P
CAS-Nummer:
Molekulargewicht:
874.24
UNSPSC-Code:
41141825
NACRES:
NA.25

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 1 mg (810606P-1mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 810606P

Lipid-Typ

phospholipids
ESR probes

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline (16:0 Tempo PC) is a spin label phospholipid, where TEMPO moiety is attached to phosphocholine headgroup.

Anwendung

1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline (16:0 Tempo PC) may be used:
  • as a spin-labeled quencher in liposomes to determine fluorophore depth
  • as spin-labeled phospholipid along with 1,2-dimyristoyl(d54)-sn-glycero-3-phosphocholine-1,1,2,2-d4-N,N,N-trimethyl-d9 (DMPC-d67) to label lidocaine for paramagnetic relaxation measurements
  • as a spin label to investigate the dependence of the packing and polarity of 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC) bilayers with temperature or as quenchers of the Laurdan fluorescence to study the Laurdan position in fluid bilayers

Biochem./physiol. Wirkung

1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline (16:0 Tempo PC/Tempo-PCSL) can effectively repress Laurdan fluorescence and can also quench the emission of long wavelength state.

Verpackung

5 mL Clear Glass Sealed Ampule (810606P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

No data available

Flammpunkt (°C)

No data available


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Cíntia C De Vequi-Suplicy et al.
Journal of fluorescence, 16(3), 431-439 (2006-06-23)
Laurdan (2-dimethylamino-6-lauroylnaphthalene) is a hydrophobic fluorescent probe widely used in lipid systems. This probe was shown to be highly sensitive to lipid phases, and this sensitivity related to the probe microenvironment polarity and viscosity. In the present study, Laurdan was
Alexander Kyrychenko et al.
The Journal of membrane biology, 253(1), 73-77 (2019-09-22)
The characterization of the behavior of lipid-attached spin probes in a bilayer is of fundamental importance for correct interpretation of the results of both EPR and fluorescence studies of protein-membrane interactions. The knowledge of the immersion depth of TEMPO spin
Victor Vasquez-Montes et al.
Biochimica et biophysica acta. Proteins and proteomics, 1867(7-8), 691-700 (2019-04-21)
Bcl-xL is a member of the Bcl-2 family of apoptotic regulators, responsible for inhibiting the permeabilization of the mitochondrial outer membrane, and a promising anti-cancer target. Bcl-xL exists in the following conformations, each believed to play a role in the
Diego E Sastre et al.
The Journal of biological chemistry, 295(7), 2136-2147 (2019-12-05)
PlsX plays a central role in the coordination of fatty acid and phospholipid biosynthesis in Gram-positive bacteria. PlsX is a peripheral membrane acyltransferase that catalyzes the conversion of acyl-ACP to acyl-phosphate, which is in turn utilized by the polytopic membrane
Nicole Weizenmann et al.
Biochimica et biophysica acta, 1818(12), 3010-3018 (2012-07-31)
The membrane location of the local anesthetics (LA) lidocaine, dibucaine, tetracaine, and procaine hydrochloride as well as their influence on phospholipid bilayers were studied by ³¹P and ¹H magic-angle spinning (MAS) NMR spectroscopy. The ³¹P NMR spectra of the LA/lipid

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