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H57807
4-Hydroxychinazolin
98%
Synonym(e):
4-Chinazolinol
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5 G
36,00 €
About This Item
Empirische Formel (Hill-System):
C8H6N2O
CAS-Nummer:
Molekulargewicht:
146.15
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
Empfohlene Produkte
Qualitätsniveau
Assay
98%
mp (Schmelzpunkt)
216-219 °C (lit.)
SMILES String
O=C1NC=Nc2ccccc12
InChI
1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)
InChIKey
QMNUDYFKZYBWQX-UHFFFAOYSA-N
Angaben zum Gen
mouse ... Parp2(11546)
Verwandte Kategorien
Signalwort
Warning
H-Sätze
P-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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Marwa F Ahmed et al.
Archiv der Pharmazie, 348(7), 487-497 (2015-04-30)
Fifteen new derivatives of quinazolin-4-one bearing the 2-furyl moiety at position 2 and a substituted phenyl moiety at position 3 were designed and synthesized to be evaluated as cytotoxic agents. Their chemical structures were confirmed by spectral and elemental analysis;
Balazs Veres et al.
The Journal of pharmacology and experimental therapeutics, 310(1), 247-255 (2004-03-05)
Activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) is involved in numerous pathophysiological conditions. Because PARP-1 knockout mice are resistant to endotoxin-induced shock and inhibitors of the enzyme were reported to have similar beneficial properties, we investigated the effect of
Francisco Javier Martín-Romero et al.
Journal of neurochemistry, 82(3), 705-715 (2002-08-03)
From 1 to 3 h after the onset of cerebellar granule cells (CGC) apoptosis in a low-K+(5 mm KCl) medium there was a large decay of NADH and a 2.5-fold increase of the rate of reactive oxygen species (ROS) production
Y J Lee et al.
Free radical biology & medicine, 29(7), 684-692 (2000-10-18)
Oxidants such as H(2)O(2) can induce a low level of apoptosis at low concentrations but at higher concentrations cause necrosis. Higher concentrations of H(2)O(2) also inhibit the induction of apoptosis by chemotherapy drugs. One theory is that, at higher concentrations
L Li et al.
Biomedical chromatography : BMC, 8(3), 145-147 (1994-05-01)
Determination of 4(3H)-quinazolinone, a newly found antiviral and immunopatentiating constituent was proposed as a method of evaluating the quality of two antiviral Chinese herbal drugs Daqingye (Folium Strobilanthis) and Banlangen(Radix Strobilanthis) and their preparations ('Antipyretic and common cold granules', 'Banlangen
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