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Merck

D5392

Sigma-Aldrich

Dithiodiglykolsäure

≥98%

Synonym(e):

2,2′-Dithiodiacetic acid

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About This Item

Empirische Formel (Hill-System):
C4H6O4S2
CAS-Nummer:
Molekulargewicht:
182.22
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

Assay

≥98%

Form

powder

Lagertemp.

−20°C

SMILES String

OC(=O)CSSCC(O)=O

InChI

1S/C4H6O4S2/c5-3(6)1-9-10-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChIKey

DLLMHEDYJQACRM-UHFFFAOYSA-N

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Verwandte Kategorien

Anwendung

  • Enhancement of octacalcium phosphate via Dithiodiglycolic acid: Research on the interlayer expansion of octacalcium phosphate illustrates the forced oxidation of Dithiodiglycolic acid intercalated molecules within its interlayers, showcasing a novel application in material science and chemical engineering (Sugiura et al., 2023).
  • Drug delivery systems: A study on redox-responsive self-assembly PEG nanoparticles enhanced by triptolide, where Dithiodiglycolic acid plays a critical role, demonstrates its potential in improving the efficacy of antitumor treatments, providing insights into pharmaceutical applications (Wang et al., 2018).
  • Synthesis and medicinal applications: A comprehensive study on the synthesis and biological evaluation of Dithiodiglycolic acid derivatives via oxidative coupling of thiols highlights its utility in medicinal chemistry, offering new avenues for drug design and development (Bakulina et al., 2019).
  • Redox-sensitive coordination polymers: The development of redox-sensitive nanoscale coordination polymers for drug delivery and cancer theranostics utilizes Dithiodiglycolic acid, providing significant advancements in cancer treatment strategies (Zhao et al., 2017).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Curcumin (CUR), a nontoxic natural compound with potent antitumor activity, was limited in clinical application due to its insolubility and exceedingly low bioavailability. In this study, a novel prodrug-nanoparticle (CSSV/TPGS-NPs) self-assembled by co-nanoprecipitation of CUR-s-s-vitamin E conjugate and d-alpha-tocopheryl polyethylene
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International journal of pharmaceutics, 575, 118980-118980 (2020-01-04)
Cardiac glycosides (CGs) have been used to treat cancer for hundreds of years. However, the narrow therapeutic window and system toxicity have hindered their wide clinical applications. Herein, the small molecule prodrug strategy and nanotechnology were integrated into one drug
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International journal of pharmaceutics, 555, 270-279 (2018-11-25)
The anti-tumor efficacy of curcumin can be markedly improved by nano-drug self-delivery systems with high drug loading capacity and smart stimulus-triggered drug release in tumor cells. Herein, a type of novel, glutathione (GSH)-responsive, PEGylated prodrug nano-micelles (PPNMs) was prepared by
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Engineered Terahertz (THz) metamaterials presented an unique characteristics for biosensing application due to their accurately tunable resonance frequency, which is in accord with vibrational frequency of some important biomolecules such as cancer biomarker. However, water absorption in THz regime is

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