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D161802

Sigma-Aldrich

1,2-Dimethylhydrazin -dihydrochlorid

98%

Synonym(e):

1,2-Dimethylhydrazin-dihydrochlorid, N,N′-Dimethylhydrazin (sym.)

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About This Item

Lineare Formel:
CH3NHNHCH3 · 2HCl
CAS-Nummer:
306-37-6
Molekulargewicht:
133.02
Beilstein:
3905684
EG-Nummer:
206-183-5
MDL-Nummer:
MFCD00012522
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24893498
NACRES:
NA.22

Assay

98%

Form

crystals

mp (Schmelzpunkt)

167-169 °C (dec.) (lit.)

SMILES String

Cl[H].Cl[H].CNNC

InChI

1S/C2H8N2.2ClH/c1-3-4-2;;/h3-4H,1-2H3;2*1H

InChIKey

WLDRFJDGKMTPPV-UHFFFAOYSA-N

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Biochem./physiol. Wirkung

Induces colon cancer in rats and mice.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Hisako Hori et al.
Regulatory toxicology and pharmacology : RTP, 112, 104578-104578 (2020-01-15)
Genotoxicity occurring at the target organs of carcinogenesis is important for understanding the mechanisms of chemical carcinogenicity and also for setting of threshold estimation. In vivo gene mutations have been evaluated by transgenic animal models in which any organ can
Vijay L Kumar et al.
Drug development research, 80(8), 1089-1097 (2019-09-01)
Anti-inflammatory drugs are well known to reduce the risk of colon cancer and prophylactic use of such agents is gaining acceptance as a cancer prevention therapy. As artesunate, an antimalarial drug, has been shown to exhibit chemopreventive properties, the present
Reema Narayan et al.
Carbohydrate polymers, 261, 117893-117893 (2021-03-27)
Glycosylated pH-sensitive mesoporous silica nanoparticles (MSNs) of capecitabine (CAP) were developed for targeting colorectal cancer. The MSNs possessed an average pore diameter of 8.12 ± 0.43 nm, pore volume of 0.73 ± 0.21 cm3/g, and particle size of 245.24 ±
Preety Ghanghas et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 78, 239-247 (2016-02-24)
Non-steroidal anti-inflammatory drugs (NSAIDs) are emerging as novel chemopreventive agents against a variety of cancers owing to their capability in blocking the tumor development by cellular proliferation and by promoting apoptosis. Inflammation is principal cause of colon carcinogenesis. A missing
Layal Slika et al.
Materials science & engineering. C, Materials for biological applications, 109, 110550-110550 (2020-04-02)
Curcumin (CUR) is a natural polyphenol present in the rhizomes of Curcuma longa and possesses diverse pharmacological effects, especially anti-carcinogenic effects against several types of cancers. Unfortunately, this novel compound has poor aqueous solubility and bioavailability that limit its pharmaceutical
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