CDS022536

Lenalidomide

• Synonym(e): 3-(7-Amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
• Empirische Formel (Hill-System): C₁₃H₁₃N₃O₃
• Molekulargewicht: 259.26
• MDL-Nummer: MFCD07772307
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329795811

Eigenschaften

• Beschreibung: Aldrich^CPR
• Form: powder
• SMILES String: O=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC=C3N
• InChI: 1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
• InChIKey: GOTYRUGSSMKFNF-UHFFFAOYSA-N
• Angaben zum Gen: human ... CRBN(51185) , CUL4A(8451) , DDB1(1642) , RBX1(9978)

Beschreibung

Anwendung

Lenalidomide is a structural analog of thalidomide, which exhibits excellent anticancer activity against multiple myeloma.[1][2] It can be used in synthesizing multiple derivatives of lenalidomide to study their biological activity.[3] Synthesis of gelator containing lenalidomide, which forms stable gels in 1,4-dioxane has been reported.[4]

Sonstige Hinweise

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Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Warning
• H-Sätze: H361d,H373
• P-Sätze: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 2 - STOT RE 2
• Zielorgane: Blood
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable