B3253

Butyrylthiocholiniodid

≥98%

• Synonym(e): (2-Mercaptoethyl)trimethylammonium-iodid-butyrat
• Lineare Formel: (CH₃)₃N(I)CH₂CH₂SCOCH₂CH₂CH₃
• CAS-Nummer: 1866-16-6
• Molekulargewicht: 317.23
• Beilstein: 3729509
• EG-Nummer: 217-475-7
• MDL-Nummer: MFCD00011845
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 57653930
• NACRES: NA.22

Eigenschaften

• Assay: ≥98%
• Form: powder
• mp (Schmelzpunkt): 171-174 °C (lit.)
• Lagertemp.: −20°C
• SMILES String: [I-].CCCC(=O)SCC[N+](C)(C)C
• InChI: 1S/C9H20NOS.HI/c1-5-6-9(11)12-8-7-10(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1
• InChIKey: WEQAAFZDJROSBF-UHFFFAOYSA-M

Beschreibung

Allgemeine Beschreibung

Butyrylthiocholine iodide is a sulfur-containing analog of butyrylcholine. It is used as a reagent for the determination of butyrylcholinesterase activity.

Anwendung

• Label-Free and Ultrasensitive Detection of Butyrylcholinesterase: A study demonstrated the use of Mn(II)-based electron spin resonance spectroscopy for the ultrasensitive detection of butyrylcholinesterase, using Butyrylthiocholine iodide as a substrate to quantify enzyme activity in the presence of organophosphorus pesticides, crucial for biochemical assay applications (Tang et al., 2022).
• Novel Nanozyme for Biosensing: Research developed a Co, N co-doped porous carbon-based nanozyme, demonstrating its utility as an oxidase mimic for fluorescence and colorimetric biosensing of butyrylcholinesterase, employing Butyrylthiocholine iodide as a key substrate, relevant in enzyme kinetics analysis (Sun et al., 2022).
• Detection System for Anti-Alzheimer′s Drug Screening: A fluorescent platform was constructed using copper nanoclusters and MnO2 nanosheets for the detection of butyrylcholinesterase activity, utilizing Butyrylthiocholine iodide, which may facilitate the screening of anti-Alzheimer′s drugs and probe cholinergic system interactions (Chen et al., 2022).
• Dual-Channel Detection of Butyrylcholinesterase: A study introduced bifunctional metal-organic frameworks with integrated fluorescence and oxidase activities, developed for dual-channel detection of butyrylcholinesterase using Butyrylthiocholine iodide, enhancing methodologies in biochemical assays (Wang et al., 2022).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves