746061

Difluormethyl-2-Pyridylsulfon

97% (HPLC)

• Synonym(e): 2-(Difluormethylsulfonyl)-pyridin, 2-PySO₂CF₂H
• Empirische Formel (Hill-System): C₆H₅F₂NO₂S
• CAS-Nummer: 1219454-89-3
• Molekulargewicht: 193.17
• Beilstein: 20317604
• MDL-Nummer: MFCD17010193
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 329765740
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97% (HPLC)
• Form: solid
• mp (Schmelzpunkt): 44-49 °C
• Funktionelle Gruppe: fluoro; sulfone
• SMILES String: O=S(C1=CC=CC=N1)(C(F)F)=O
• InChI: 1S/C6H5F2NO2S/c7-6(8)12(10,11)5-3-1-2-4-9-5/h1-4,6H
• InChIKey: YRQNSTAWTLXCEZ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Difluoromethyl 2-pyridyl sulfone (2-PySO₂CF₂H) is a reagent used in the gem-difluoroolefination of aldehydes and ketones. It is also used as a reagent in the nucleophilic difluoro(sulfonato)methylation of alcohols, N-sulfinyl imines, and halides.[1][2]

Anwendung

Reagent is used in the olefination of ketones and aldehydes to form gem-difluoro olefins under basic conditions.[3] Product is also used as a crucial intermediate toward making 1,1-difluorinated alkyl chains for the alkylation of heterocycles.[4]

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301,H319
• P-Sätze: P264 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313 - P405
• Gefahreneinstufungen: Acute Tox. 3 Oral - Eye Irrit. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable