68571
Aminomethyl ChemMatrix® Harz
0.50-0.70 mmol/g loading (amine)
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About This Item
UNSPSC-Code:
12352200
NACRES:
NA.22
Empfohlene Produkte
Produktlinie
ChemMatrix®
Form
crystals
Eignung der Reaktion
reaction type: Fmoc solid-phase peptide synthesis
Partikelgröße
100-200 mesh
Kapazität
0.50-0.70 mmol/g loading (amine)
Anwendung(en)
peptide synthesis
Funktionelle Gruppe
amine
Lagertemp.
2-8°C
Allgemeine Beschreibung
Aminomethyl ChemMatrix® resin is a polyethyleneglycol (PEG)-based resin, composed of highly cross-linked primary ether bonds, therefore the resin is chemically and mechanically stable in a broad range of solvents. It has good loading properties when compared to other PEG resins due to its availability in free-flowing powder form. This resin is also more effective than polystyrene resins in the synthesis of hydrophobic or highly structured polypeptides.[1][2]
Anwendung
Aminomethyl ChemMatrix® resin can be used as efficient support in solid-phase peptide synthesis (SPPS).[2][3] It is also used as a starting material to synthesize dihydrolipoyl-supported polymer, which is used as an efficient and recyclable reducing agent for the reduction of disulfide compounds.[4]
Rechtliche Hinweise
ChemMatrix is a registered trademark of Matrix Innovation, Inc.
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Convenient supported recyclable material based on dihydrolipoyl-residue for the reduction of disulfide derivatives
Bienvenu C, et al.
Tetrahedron Letters, 51(25), 3309-3311 (2010)
ChemMatrix for complex peptides and combinatorial chemistry.
Garcia-Ramos Y, et al.
Journal of Peptide Science, 16(12), 675-678 (2010)
Polyethyleneglycol-based resins as solid supports for the synthesis of difficult or long peptides
Beatriz G, et al.
International Journal of Peptide Research and Therapeutics, 13(1-2), 265-270 (2007)
Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins
Gerardo A Acosta, et al.
Journal of Peptide Science, 15(10), 629-633 (2009)
Artikel
ChemMatrix® is a proprietary, 100% PEG (polyethylene glycol) based resin from PCAS BioMatrix.
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