541524

5,5-Dimethyl-1,3,2-dioxaphosphorinan-2-on

96%

• Synonym(e): 2,2-Dimethylpropane-1,3-diol cyclic phosphonate, Cyclic 2,2-dimethyltrimethylene phosphonate, Neopentylene phosphite, Neopentylglycol hydrogen phosphite
• Empirische Formel (Hill-System): C₅H₁₁O₃P
• CAS-Nummer: 4090-60-2
• Molekulargewicht: 150.11
• EG-Nummer: 223-832-8
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24878543
• NACRES: NA.22

Eigenschaften

• Assay: 96%
• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• mp (Schmelzpunkt): 51-56 °C (lit.)
• SMILES String: CC1(C)CO[PH](=O)OC1
• InChI: 1S/C5H11O3P/c1-5(2)3-7-9(6)8-4-5/h9H,3-4H2,1-2H3
• InChIKey: QHXZLTUNAVKFIT-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for:

• Palladium(I) catalyzed addition of P(O)-H bonds
• Highly regioselective modified Pudovik addition reaction
• Radical reactions mediated by manganese(III) acetate
• Stable cyclic DEPMPO derivatives as mechanistic markers of stereoselective hydroxyl radical adduct formation in biological systems
• Copper-catalyzed aerobic oxidative dehydrogenative coupling reactions
• Bisphosphonates/phosphanamidates as anticancer agents

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 228.9 °F - closed cup
• Flammpunkt (°C): 109.4 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges