375098

6-Chlorchinolin

99%

• Empirische Formel (Hill-System): C₉H₆ClN
• CAS-Nummer: 612-57-7
• Molekulargewicht: 163.60
• EG-Nummer: 210-314-1
• MDL-Nummer: MFCD00024024
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24863364
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Form: solid
• bp: 126-127 °C/10 mmHg (lit.)
• mp (Schmelzpunkt): 41-43 °C (lit.)
• Funktionelle Gruppe: chloro
• SMILES String: Clc1ccc2ncccc2c1
• InChI: 1S/C9H6ClN/c10-8-3-4-9-7(6-8)2-1-5-11-9/h1-6H
• InChIKey: GKJSZXGYFJBYRQ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

6-Chloroquinoline is a haloquinoline. Pd/C-catalyzed Suzuki-Miyaura coupling of 6-chloroquinoline with 2-(dicyclohexylphosphino)biphenyl is reported.[1] The polarographic behavior of 6-chloroquinoline in DMF solutions and mechanism of its reduction at the dropping mercury electrode has been reported.[2] Stability constants of molecular iodine complexes of 6-chloroquinoline in aliphatic and aromatic hydrocarbons, carbon tetrachloride, bromobenzene and chloro-substituted benzenes was investigated by spectrophotometric methods.[3]

The standard molar enthalpy of formation of 6-chloroquinoline has been derived from the standard molar enthalpy of combustion and was evaluated in terms of molecular structure.[4] Its arylation reaction with diamine derivatives of adamantanes in the presence of palladium catalyst has been reported to afford N,N′-diaryl derivatives.[5]

Anwendung

Catalyst for high yield preparation of ethoxycarbonyl isothiocyanate.[6]

6-Chloroquinoline may be used in the synthesis of 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine.[7] It may be used as catalyst for high yield preparation of ethoxycarbonyl isothiocyanate.[6]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves