348007

1-Trimethylsilyl-1-hexin

99%

• Lineare Formel: CH₃(CH₂)₃C≡CSi(CH₃)₃
• CAS-Nummer: 3844-94-8
• Molekulargewicht: 154.32
• Beilstein: 1421652
• MDL-Nummer: MFCD00075407
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24861541
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Brechungsindex: n20/D 1.431 (lit.)
• bp: 65 °C/35 mmHg (lit.)
• Dichte: 0.764 g/mL at 25 °C (lit.)
• SMILES String: CCCCC#C[Si](C)(C)C
• InChI: 1S/C9H18Si/c1-5-6-7-8-9-10(2,3)4/h5-7H2,1-4H3
• InChIKey: SFCRJYVNDZSYCT-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1-Trimethylsilyl-1-hexyne is a trialkylsilylalkyne. Tetrabutylammonium fluoride (TBAF) catalyzed conversion of 1-trimethylsilyl-1-hexyne to corresponding propargylic alcohol is reported.[1] Pd(OAc)₂/L‚ HCl-catalyzed Sonogashira coupling reaction of aryl bromide with 1-trimethylsilyl-1-hexyne has been reported.[2]

Anwendung

1-Trimethylsilyl-1-hexyne may be used in the preparation of enynes by coupling with vinyl triflates or aryl iodide using silver salt and Pd(PPh₃)₄ as catalyst_.[3] It may be used in the preparation of functionalised durene and isodurene derivatives.[4]

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Warning
• H-Sätze: H226,H315,H319,H335
• P-Sätze: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 122.0 °F - closed cup
• Flammpunkt (°C): 50 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter