Smoking is a major risk factor for endothelial cell injury and subsequent coronary artery disease. Epidemiological studies implicate the phospholipase A2/arachidonic acid cascade in the mechanism by which smoking causes heart disease. However, specific components of cigarette smoke that activate

Cigarette smoke components inhibited intercellular communication and differentiation in human pancreatic ductal epithelial cells.

Mei-Hui Tai et al.

International journal of cancer, 120(9), 1855-1862 (2007-02-03)

Smoking is a well-documented risk factor for the development of pancreatic adenocarcinoma. Although the most abundant polycyclic aromatic hydrocarbons (PAHs) in cigarette smoke are methylated anthracenes and phenanthrenes, the epigenetic toxicity of these compounds has not been extensively studied. We

Capillary gas chromatography/pulsed supersonic jet/fluorescence excitation spectroscopy for the identification of methylanthracenes in a complex environmental sample.

B V Pepich et al.

Analytical chemistry, 58(13), 2825-2830 (1986-11-01)

Infrared spectra of substituted polycylic aromatic hydrocarbons.

S R Langhoff et al.

The journal of physical chemistry. A, 102(9), 1632-1646 (2001-09-07)

Calculations are carried out using density functional theory (DFT) to determine the harmonic frequencies and intensities of 1-methylanthracene, 9-methylanthracene, 9-cyanoanthracene, 2-aminoanthracene, acridine, and their positive ions. The theoretical data are compared with matrix-isolation spectra for these species also reported in

Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine-specific phospholipase C.

Brad L Upham et al.

Cancer science, 99(4), 696-705 (2008-04-02)

Inhibition of gap junctional intercellular communication (GJIC) and the activation of intracellular mitogenic pathways are common hallmarks of epithelial derived cancer cells. We previously determined that the 1-methyl and not the 2-methyl isomer of anthracene, which are prominent cigarette smoke

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1-Methylanthracen

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Eigenschaften

Assay

bp

mp (Schmelzpunkt)

SMILES String

Sicherheitshinweise

Lagerklassenschlüssel

WGK

Flammpunkt (°F)

Flammpunkt (°C)

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Analysenzertifikate (COA)

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