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Sigma-Aldrich

2,3-Dimercapto-1-propanoltributyrat

97%

Synonym(e):

BAL Tributyrat

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About This Item

Lineare Formel:
CH3CH2CH2CO2CH2CH(SCOCH2CH2CH3)CH2SCOCH2CH2CH3
CAS-Nummer:
58428-97-0
Molekulargewicht:
334.49
MDL-Nummer:
MFCD00010601
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24857046
NACRES:
NA.22

Assay

97%

Form

liquid

Brechungsindex

n20/D 1.495 (lit.)

bp

156-160 °C/0.15 mmHg (lit.)

Dichte

1.083 g/mL at 25 °C (lit.)

SMILES String

CCCC(=O)OCC(CSC(=O)CCC)SC(=O)CCC

InChI

1S/C15H26O4S2/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3

InChIKey

NHBKXEKEPDILRR-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

2,3-Dimercapto-1-propanol tributyrate is a thioester analog of triacylglycerol and has been used:
  • in lipase inhibition assay during in vitro screening of medicinal plants as antidiabetics with glucosidase and lipase inhibitory activities
  • in colorimetric microplate assay for lipase activity
  • to analyze positional specificity of LipG (lipase-encoding gene) toward triacylglycerol by a simple continuous spectrophotometric method

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

235.4 °F - closed cup

Flammpunkt (°C)

113 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Guillermo Ramírez et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 701261-701261 (2012-10-20)
This work shows the inhibitory effect on glucosidase and lipase enzymes of 23 medicinal plants described as traditional treatments for diabetes in several Mexican sources. Hydroalcoholic extracts of selected plants were evaluated at 1 mg/mL for glucosidase and 0.25 mg/mL for lipase
S Lombard et al.
The Biochemical journal, 358(Pt 3), 773-781 (2001-09-06)
The present study was carried out with a view of determining ricin lipolytic activity on neutral lipids in emulsion and in a membrane-like model. Using 2,3-dimercapto-1-propanol tributyrate (BAL-TC(4)) as substrate, the lipolytic activity of ricin was found to be proportional
Mi-Hwa Lee et al.
Applied and environmental microbiology, 72(11), 7406-7409 (2006-09-05)
We cloned lipG, which encoded a lipolytic enzyme, from a Korean tidal flat metagenomic library. LipG was related to six putative lipases previously identified only in bacterial genome sequences. These enzymes comprise a new family. We partially characterized LipG, providing
[A new simplified colorimetric assay of colipase in duodenal juice using BALB as substrate and its clinical application].
Y Furukawa et al.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 83(7), 1367-1375 (1986-07-01)
Suk-Jung Choi et al.
Journal of biochemistry and molecular biology, 36(4), 417-420 (2003-08-05)
The present work describes a colorimetric microplate assay for lipase activity based on the reaction between 5,5'-dithiobis(2-nitro benzoic acid) (DTNB) and the hydrolysis product of 2,3-dimercapto-1-propanol tributyrate (DMPTB). Reaction mixtures containing DTNB, DMPTB, and lipase were prepared in microplate wells
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