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269476

Sigma-Aldrich

N-Acetylprocainamid

≥99%

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About This Item

Lineare Formel:
4-(CH3CONH)C6H4CONHCH2CH2N(C2H5)2
CAS-Nummer:
32795-44-1
Molekulargewicht:
277.36
MDL-Nummer:
MFCD00009052
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24856329
NACRES:
NA.22
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Assay

≥99%

Form

solid

mp (Schmelzpunkt)

138-140 °C (lit.)

Löslichkeit

soluble 1%, clear, colorless to faintly yellow (1N HCl)

Funktionelle Gruppe

amide
amine

SMILES String

CCN(CC)CCNC(=O)c1ccc(NC(C)=O)cc1

InChI

1S/C15H23N3O2/c1-4-18(5-2)11-10-16-15(20)13-6-8-14(9-7-13)17-12(3)19/h6-9H,4-5,10-11H2,1-3H3,(H,16,20)(H,17,19)

InChIKey

KEECCEWTUVWFCV-UHFFFAOYSA-N

Verwandte Kategorien

Allgemeine Beschreibung

The relaxant effects of N-acetylprocainamide on bovine tracheal smooth muscle was studied[1].

Anwendung

N-acetylprocainamide (NAPA) was used as a model drug in the study of establishing a quantitative approach to predict the renal clearances of basic drugs using N-1-methylnicotinamide (NMN)[2].

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000108773
0000048589
0000045240
1328418V
1328418

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Die Dokumentenbibliothek aufrufen

Jimmy Flarakos et al.
Analytical chemistry, 77(5), 1345-1353 (2005-03-01)
High-throughput screening of combinatorial libraries has evolved from studying large diverse libraries to analyzing small, structurally similar, focused libraries. This paradigm shift has generated a need for rapid screening technologies to screen both diverse and focused libraries in a simple
Subhash Chandra Ghosh et al.
The Journal of organic chemistry, 77(18), 8007-8015 (2012-08-17)
A practical method for the amidation of aldehydes with economic ammonium chloride or amine hydrochloride salts has been developed for the synthesis of a wide variety of amides by using inexpensive copper sulfate or copper(I) oxide as a catalyst and
Amitava Dasgupta et al.
Archives of pathology & laboratory medicine, 131(7), 1094-1098 (2007-07-10)
St John's wort induces the activity of the cytochrome P450 enzyme system causing treatment failure because of increased metabolism of many drugs. Procainamide is metabolized by a different pathway to N-acetyl procainamide. To study St John's wort-procainamide interaction using a
J R Koup et al.
Therapeutic drug monitoring, 20(1), 73-77 (1998-03-05)
Procainamide hydrochloride is a Class 1A antiarrhythmic agent administered intravenously or orally for treatment of symptomatic ventricular premature depolarizations (VPD), nonsustained ventricular tachycardia, and life-threatening ventricular arrhythmias. A new sustained-release formulation, Procanbid, which allows for twice-daily dosing was recently approved
N D Eddington et al.
Biopharmaceutics & drug disposition, 19(5), 291-296 (1998-07-23)
The effect of moderate and prolonged exercise on the disposition and metabolism of drugs has not been extensively examined. The present study examined the effect of exercise training on the pharmacokinetics of procainamide and its active metabolite, N-acetylprocainamide. Male Sprague
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