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201014

Sigma-Aldrich

N-Benzylbenzamid

≥98%

Synonym(e):

Benzoic acid benzylamide, N-(Phenylmethyl)benzamide, N-Benzoylbenzylamine

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About This Item

Lineare Formel:
C6H5CONHCH2C6H5
CAS-Nummer:
1485-70-7
Molekulargewicht:
211.26
EG-Nummer:
216-063-4
MDL-Nummer:
MFCD00003070
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24851990
NACRES:
NA.22

Assay

≥98%

mp (Schmelzpunkt)

104-106 °C (lit.)

Löslichkeit

acetone: 25 mg/mL, clear, colorless

SMILES String

O=C(NCc1ccccc1)c2ccccc2

InChI

1S/C14H13NO/c16-14(13-9-5-2-6-10-13)15-11-12-7-3-1-4-8-12/h1-10H,11H2,(H,15,16)

InChIKey

LKQUCICFTHBFAL-UHFFFAOYSA-N

Verwandte Kategorien

Allgemeine Beschreibung

N-Benzylbenzamide inhibits the activity of tyrosinase.

Anwendung

A convenient precursor to α-substituted benzylamines and an indicator for the titration of butyllithium and other lithium bases. For references see Aldrichimica Acta .

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Yae Eun Chong et al.
Biomedical chromatography : BMC, 33(11), e4653-e4653 (2019-07-20)
Ondansetron, a widely used antiemetic agent, is a P-glycoprotein (P-gp) substrate and therefore expression of P-gp at the blood-brain barrier limits its distribution to the central nervous system (CNS), which was observed to be reversed by coadministration with P-gp inhibitors.
Manting Chiang et al.
Pharmaceutical research, 37(10), 205-205 (2020-09-30)
Modulation of 5-HT3 receptor in the central nervous system (CNS) is a promising approach for treatment of neuropathic pain. The goal was to evaluate the role of P-glycoprotein (Pgp) in limiting exposure of different parts of the CNS to ondansetron
Sung Jin Cho et al.
Bioorganic & medicinal chemistry letters, 16(10), 2682-2684 (2006-03-04)
A series of potent inhibitors of tyrosinase and their structure-activity relationships are described. N-Benzylbenzamide derivatives (1-21) with hydroxyl(s) were synthesized and tested for their tyrosinase inhibitory activity. With this series, compound 15 provided a potent tyrosinase inhibition: it effectively inhibited
Aldrichimica Acta, 11, 20-20 (1978)
Zsanett Dorkó et al.
Talanta, 162, 167-173 (2016-11-14)
A simple and efficient method is presented for assessing molecularly imprinted polymers (MIP) and other sorbents from the point of view of practical applications. The adsorption isotherms of the compounds, which need to be separated or detected in an application

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