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HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Synonyme:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Metoclopramid, VETRANAL®, analytical standard,
Spezies
human
Metoclopramid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Metoclopramid -hydrochlorid, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
SR 57227A, solid,
Spezies
human
Metoclopramid -hydrochlorid, solid,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
DCEBIO, ≥98% (HPLC), solid,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Serotonin -hydrochlorid, powder,
Spezies
human
Serotonin creatinine sulfate monohydrate, powder,
Spezies
human
Ondansetron -hydrochlorid Dihydrat, ≥98% (HPLC), powder,
Spezies
human
1-(4-Chlorphenyl)piperazin, ≥98.0% (GC),
Spezies
rat
Ondansetronhydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Serotonin-Rezeptor-3A/HTR3A, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Trimipramin -maleat (Salz), ≥98% (TLC), powder,
Spezies
human
Zimelidin -dihydrochlorid, solid,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Spezies
human
R-(−)-Fluoxetin -hydrochlorid, >98% (HPLC), solid,
Spezies
human
Fluoxetin -hydrochlorid, solid,
Spezies
human
Reserpin, ,
Spezies
human
Sertralin -hydrochlorid, ≥98% (HPLC),
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Spezies
human

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
5-Hydroxyindol-3-Essigsäure, ≥98% (HPLC), crystalline,
Spezies
human

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
5-Hydroxy-L-Tryptophan, powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Htr3a,
Spezies
mouse
MISSION® esiRNA, targeting human HTR3A,
Spezies
human