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Merck

BCL2L1

BCL2-like 1

Synonyme:
BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(598) Summary: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
  • Mouse(12048) BCL2-like 1
  • Rat(24888) Bcl2-like 1
  • Domestic Rabbit(100008875) BCL2-like 1
  • domestic guinea pig(100730495) BCL2-like 1
  • Zebrafish(114401) bcl2-like 1
  • cow(282152) BCL2-like 1
  • domestic cat(493701) BCL2-like 1
  • chicken(373954) BCL2-like 1
  • dog(403618) BCL2-like 1
  • sheep(443061) BCL2-like 1
  • naked mole-rat(101713410) BCL2-like 1

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Bcl-xL Antibody, clone 1O8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, canine, feline, human, monkey, mouse, porcine, rat
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Bcl-X Antibody, clone 2H12, clone 2H12, Chemicon®, from mouse,
Speziesreaktivität
human, mouse, pig, rat
Anwendung
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-BCL2L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-Bcl-XL- und -BclXs-Antikörper, Klon 7B2.5, clone 7B2.5, Chemicon®, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Bcl-xL Antibody, Phospho-specific, serum, Chemicon®,
Speziesreaktivität
human
Anwendung
western blot

Proteins

Produktnummer
Beschreibung
Spezies
Bcl-xL Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human BCL2L1,
Spezies
human
MISSION® esiRNA, targeting mouse Bcl2l1,
Spezies
mouse