1387002

Mepivacaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-Methyl-2′,6′-pipecoloxylidine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride
• Empirical Formula (Hill Notation): C₁₅H₂₂N₂O · HCl
• CAS Number: 1722-62-9
• Molecular Weight: 282.81
• NACRES: NA.24
• PubChem Substance ID: 329750362
• UNSPSC Code: 41116107
• MDL number: MFCD00144738

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: mepivacaine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl
• InChI: 1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
• InChI key: RETIMRUQNCDCQB-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Local anesthetic. Reversibly blocks transient Na⁺ inward current, as well as the steady-state K⁺ outward current.

Local anesthetic. Reversibly blocks transient Na⁺ inward current, as well as the steady-state K⁺ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H336
• pcodes: P261 - P264 - P270 - P271 - P301 + P310 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable